This article links to one that seems much more compelling.<p><a href="https://www.nature.com/articles/d41586-019-02638-w" rel="nofollow">https://www.nature.com/articles/d41586-019-02638-w</a><p>I've been thinking about aging interventions lately. My grandfather passed this year, and my grandmother is in poor shape. She's confined to a wheel chair and she's very frail.<p>Recently, while I was visiting her, she asked about where I was living now, and I told her, and she then asked me if I kept up with <My name> who also lived out there. I smiled, and said that I did, since I don't know what else to say. It hurts to remember her though compared to her current state. When she's more lucid, she talks expectantly of her coming death. Her life now is mainly sleeping and eating with occasional car ride or visit.<p>I wonder about how ethical it would or wouldn't be to treat her with an experimental aging treatment. The linked article mentions HGH, plus DHEA, and metformin, taken together, reduced 6/6 epigenetic age markers for 9/9 participants. That seems really promising.<p>I know I could get the paper and find more detailed information about the dosage. I know I could talk to doctors about the safety of it. I'm confident I could convince my grandmother's nurse to administer the additional medication...<p>It's tough to think about, because, on the one hand, I know it's weird and strange and sounds immoral for an unqualified person to run medical experiments on his grandmother. On the other hand, I also know that her current life is bad and she will soon die. It's just hard for me to conclude that waiting for her death is a better answer than experimenting.