I think that many such great thinkers have, due to circumstances and early on, have developed<p>(1) a unique, uninhibited way of looking at problems, i.e. not different from what's generally prescribed to entrepreneurs: Consider <i>every</i> possible lead, even if people say it's stupid/has been done, etc. Einstein, famously had difficulty at school as a kid, so he actually thought about many concepts that we take for granted or find silly ("what would happen if I shine a flashlight while riding a bike").<p>(2) power to concentrate on a problem. When asked how he came up with his solutions Newton said that he thought on the problem until the solution came to him. This sounds simple but embedding yourself in a problem like that is beyond most people's focusing skills (I can't go by 10 minutes without checking HN, for example).