This is classic operations research linear optimisation stuff.<p>You have an expensive two dose vaccine which has very high confidence but demands explicit temperature protocols be matched, and limited supply.<p>You have a cheap two dose vaccine with some evidence of at least 50% and probably better coverage, which can be mass produced quickly and issued to any doctor or pharmacy for use, with no stringent temperature protocol.<p>There is evidence of increased virulence in the infection.<p>The hospital system is at its breaking point operating over 100% capacity with severe staffing issues.<p>What do you do?<p>Chasing perfection when it turns out statistically giving more people a lower confidence single dose now can save more lives...<p>This is what operations research is all about.