Clearly Flu, HIV, and Nipah are more pressing, but I found myself wondering last night what the odds are of a rhinovirus vaccine being in the cards thanks to rapid progress SARS-CoV-2 has pressed us to make w.r.t. RNA and protein-like vaccines.<p>Economics is the largest barrier in my mind. While my understanding is that these vaccines are less expensive to produce, it's hard to convince people to get the flu shot, let alone a common cold shot. What's more is that with hundreds of variants, it's efficacy would be hard to get right.<p>That said, I'd gladly pay a heft amount yearly if it meant I had a >60% chance of not catching a cold that year.