Mouse studies show gene therapy can cause big drop in latent herpes infections

.. In mice.<p>It is unknown if it will work in humans. In addition, what are the long term consequences of causing multiple DNA cuts in nerve cells that the DNA repair mechanism cannot repair?<p>There is still a very long, long way to go.

<a href="https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC6917347&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC6917347&#x2F;</a><p>Just reminded myself that above frome couple years back

One could imagine this technique also working in latent reserves of coronavirus harbored by people who have become infected.

My understanding is that herpes (both HSV1 and HSV2) are not actually bad but have enormous social stigma, which is the main problem. I wonder what can be done to address that, as an alternative strategy.

That&#x27;s fantastic! If it&#x27;s successfully trialed in humans maybe they can go after HPV next. Yes, there&#x27;s a vaccine but there are many more variants than even in the latest vaccine.

I remember a study suggesting the Chickenpox vaccine suppresses outbreaks of HSV1 and HSV2 <a href="https:&#x2F;&#x2F;www.dovepress.com&#x2F;efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent--a10554" rel="nofollow">https:&#x2F;&#x2F;www.dovepress.com&#x2F;efficacy-of-the-anti-vzv-anti-hsv3...</a>

Hi! I have found this forum by google search. I see that you are talking about the research being conducted at Fred Hutch for HSV. If you still do no know, there is a Reddit Group that is in close contact with the researchers: <a href="https:&#x2F;&#x2F;www.reddit.com&#x2F;r&#x2F;HerpesCureResearch" rel="nofollow">https:&#x2F;&#x2F;www.reddit.com&#x2F;r&#x2F;HerpesCureResearch</a> I&#x27;m in the group as well, helping with moderation and awareness on this research.<p>The group has started a fundraiser with Fred Hutch less than 2 years ago, in order to extend the study further to HSV2 and guinea pig testing, beside the research on HSV1 in a mouse model, supported by the NIH. The fundraiser has had a great success and it has collected all the needed funds for the study in Guinea Pigs through the donations from many sufferers and thanks to a large donation of 250k from one person.<p>Because of this financial support that has been given, the researchers are in close contact with the reddit group that has supported their work and they communicate with them periodically during the year on the various milestones, sometimes to single members that are representative for the initiative, sometimes with an online meeting with questions and answers from all the participants.<p>If you are interested in following more closely this research, you can join the group. The next milestones for this year are the communication between Fred Hutch and the FDA, to find agreements on starting clinical trials at the end 2023 - beginning 2024. After this, the reddit group will receive an update from these agreements and suggestions on how to support Fred Hutch further. At the end of summer the results of the study on Guinea Pigs will be presented to us.<p>There are also opportunities of volunteering for the research group for the ones that live closer to their area.<p>Know that this research is very active and it is aimed at reaching clinical trials and the market.<p>Beside this, you will find many other informations on the website, like the similar research being conducted by ExcisionBio, in collaboration with Fred Hutch. And the clinical trial being done in China. Communications with Dr.Friedman on a therapeutic application of his vaccine and updates on clinical trials for herpes being conducted by other companies.

&gt; Nevertheless, she persisted.<p>As a complete aside, I think this is a really interesting example of how a particular phrase has become part of the cultural vernacular. From the floor of the United States Congress, to t-shirts, to an article on herpes research. Pretty cool, imho.

Can we get mRNA vaccine to Herpes

What bothers me is that every single good news coming from science has the same old &quot;but&quot;.<p>&gt;It will still take a long time before these experiments lead to the first human trials<p>And we&#x27;ll never hear from them again. You betcha!