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Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

469 点作者 lazycrazyowl超过 4 年前

18 条评论

scrollaway超过 4 年前
Israel feels like the only nation taking the importance and urgency of vaccination seriously.<p>Here in Europe, articles are coming out complaining that the slow vaccination could be harming the economy which, well, fucking duh. (<a href="https:&#x2F;&#x2F;www.brusselstimes.com&#x2F;news&#x2F;belgium-all-news&#x2F;154626&#x2F;coronavirus-slow-vaccination-campaign-could-cost-europe-close-to-90-billion-euros&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.brusselstimes.com&#x2F;news&#x2F;belgium-all-news&#x2F;154626&#x2F;c...</a>)<p>Fast rollout. Involve pharmacies. Involve the army. Distribute widely and efficiently. Prepare for months before the vaccine is here. Follow-up campaign to convince vax holdouts. A real War Effort.<p>There&#x27;s barely any calls for volunteering here in Belgium. Hospitals and vaccination centers will complain to the government that they are understaffed but you seldom hear them urgently asking for new volunteers to assign to COVID teams and vaccination centers. We spent a ton of time debating whether the social bubble should be 2 or 3 large, whether kids should be 12 or 14 before they count for it, etc etc and those spending that time were the same people who didn&#x27;t prepare for the eventuality of a vaccine, and started doing so in late December.<p>Sorry this has veered off topic. The number of articles that can be summed up to &quot;Vaccines work, are good, and israel is doing it right&quot; frustrate little european me. :(
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jansan超过 4 年前
The Google COVID-19 statistics for Israel show that cases and deaths are declining, but not at a faster rate than elsewhere in the world. Reported deaths lag behind sometimes for weeks and new deaths were caused by infections weeks ago, so vaccination may not have much effect on deaths, yet. But the number of positive tests should have gone down considerably with 50% of the population vaccinated. Are all these aymptomatic cases or do the is this due to part of the population not keeping any rules? Does anybody have information why the numbers are sill that high?
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gregwebs超过 4 年前
The vaccine has 95% efficacy in initial controlled trials. It is almost impossible to reach (within 1%) of that same level of effectiveness in the real world as claimed here. The real world has a big chunk of the population with an immune system that doesn&#x27;t respond nearly as well to the vaccine (such as the elderly).<p>Here is an overview of an Israeli study that was finding a more realistic effectiveness of 70% <a href="https:&#x2F;&#x2F;dalewharrison.substack.com&#x2F;p&#x2F;israeli-vaccination-data" rel="nofollow">https:&#x2F;&#x2F;dalewharrison.substack.com&#x2F;p&#x2F;israeli-vaccination-dat...</a><p>If anyone has a link to the actual study, please post it! It is really annoying to see news articles posted about studies that don&#x27;t link to them or even provide any basic information to find the study.
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lucd超过 4 年前
Here is some chart showing vaccination effect on hospitalization for severe forms. Very telling.<p><a href="https:&#x2F;&#x2F;ourworldindata.org&#x2F;grapher&#x2F;israel-severe-hospitalizations-age?tab=chart&amp;stackMode=relative&amp;time=2021-01-08..latest&amp;country=Early%20vaccinated-0~Late%20vaccinated-0~Late%20vaccinated-1&amp;region=World" rel="nofollow">https:&#x2F;&#x2F;ourworldindata.org&#x2F;grapher&#x2F;israel-severe-hospitaliza...</a>
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eganist超过 4 年前
Someone&#x27;s comment raising fear about unmitigated transmission risk got flagged to death, so here&#x27;s the comment I originally wrote in response to it:<p><a href="https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2021.02.06.21251283v1" rel="nofollow">https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2021.02.06.21251283v...</a><p>The most recent un-reviewed publication looking into viral load, which is likely associated with the risk of transmission.<p>Lay reading: <a href="https:&#x2F;&#x2F;www.theguardian.com&#x2F;science&#x2F;2021&#x2F;feb&#x2F;09&#x2F;pfizerbiontech-covid-vaccine-reducing-viral-load-data-israel-suggests" rel="nofollow">https:&#x2F;&#x2F;www.theguardian.com&#x2F;science&#x2F;2021&#x2F;feb&#x2F;09&#x2F;pfizerbionte...</a>
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dzhiurgis超过 4 年前
Is there Any data yet if people are contagiuos when vaccinated and infected?
lukeitup超过 4 年前
That is some well needed news! Just hope that Europe will speed up its vaccine distribution now.
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heyuji78超过 4 年前
Does the data only show that those individuals do not develop symptoms, but can potentially spread the virus to non-vaccinated individuals? Or does the 94% drop in symptomatic infections also means that those individuals can no longer spread the virus to others?
code-scope超过 4 年前
Anyone know if the similar mRNA process can be used to create vaccine for normal FLU virus.
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mschuster91超过 4 年前
&gt; He added that the data indicates the Pfizer vaccine, which was developed in partnership with Germany’s BioNTech, is even more effective two weeks or more after the second shot.<p>That&#x27;s wrong. BioNTech was the developer, Pfizer only was pulled in for manufacturing and clinical tests.
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baybal2超过 4 年前
Reassuring news! A hope for some normalcy coming with ongoing vaccinations.
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EdwinLarkin超过 4 年前
With the number of lockdowns in Europe it feels like a spit to the face for all of the businesses and tax payers in Europe.<p>Even throwing more money at the problem sounds better than not doing anything but I wish the EU would have forced Pfizer&#x2F;Biontech and other pharma companies to just produce the vaccine en masse.<p>This is a war time and only those that cant fight back are forced to suck it up.
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Ulrich2超过 4 年前
The side effect of this amazing BioNTech&#x2F;Pfizer success: Meanwhile AstraZeneca is clearly only the second choice. At least locally here in my town (EU) people line up for Biontech, but the vaccination centers that offer AstraZeneca report up to 50% no shows.
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ancymon超过 4 年前
As I understand, for example in Europe Pfizer is producing vaccines in single factory and not in sufficient number. Why production doesn&#x27;t happen in more places? Couldn&#x27;t they sell license to other European pharmaceutical companies to produce it? Is production process so unique it can&#x27;t be replicated in other places?
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helge9210超过 4 年前
Being an Israeli I wouldn&#x27;t trust anything coming from Israel related to COVID-19.<p>Current government is practically crime syndicate, all the decisions related to COVID-19 are made secret for at least 30 years, agreement with Pfizer is mostly secret, case number is manipulated by gauging tests conducted and selecting appropriate population groups and vaccines are forced on population under pain of limiting access to work, grocery and flights abroad.
zyxzevn超过 4 年前
Congratulations, but some sceptical notes.<p>The spring is coming, ending the wave like last year. This can reduce the cases by a similar amount. We will have to wait till next season what will happen. The sun and season has a dramatic influence on Covid. We saw that last year. Related with vitamin-D and ultra-violet radiation.<p>Recently some countries had changes in PCR tests. Austria had a similar reduction after not using the PCR tests. They had 95% false positives on PCR, compared to other tests. The PCR is problematic due to the usage of far too many cycles. When testing random persons, it gives 95% false positives over 35 cycles, but many countries even use 45 cycles or more. Sadly, using too many cycles is not scientific evidence for anything.<p>Many countries also reached a natural herd immunity. Sweden is now very close to getting 60% anti-body herd immunity. Besides that we have T-cell herd-immunity of which we do not know that much. I already had covid, got my anti-bodies &amp; T-cell-immunity and am now fully immune.<p>Probably not applicable to Israel. Certain countries use cheap old-school medicine that prevent the disease. Like India and Ghana. Changes in medicine-use give similar changes in cases. If you don&#x27;t believe it, just talk to some people that live there. They do not have a covid problem. IMHO this is the best but least profitable way to deal with the disease.<p>Controversial: The vaccines can give strong fevers. This is a well known side-effect. These might have thinned out the weakest people. Which now did not catch covid. While I think the effect is small, it can give a temporary reduction of the cases. I hope the medicine companies will improve the vaccines, so we do not get these side-effects.<p>The difference between these can be subtle and depends on raw data. But statistical analysis can already show some details.
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TedPetrou超过 4 年前
Israel is experiencing very high excess deaths with respect to its elderly in 2021 (see euroMOMO <a href="https:&#x2F;&#x2F;www.euromomo.eu&#x2F;graphs-and-maps&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.euromomo.eu&#x2F;graphs-and-maps&#x2F;</a>)<p>This is despite over 80% of its 70+ age group having both doses of the vaccine. At least half of the 70+ were fully vaccinated by January 23rd.<p>It is the elderly all cause mortality that ultimately matters to me. If elderly are dying of other causes, then there are problems.<p>Regardless, 2021 elderly mortality in Israel will serve as a good test for the vaccine as the vast majority of 70+ will be fully vaccinated for nearly the entire year.
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kesor超过 4 年前
It is worth adding that the Israeli government is <i>very</i> aggressively pushing vaccination. So aggressively that there is a notable movement of people who oppose to get vaccinated because of the blatant violations to basic human rights in a democratic country.<p>At the very beginning of vaccination in Israel the demand was very high, since all those waiting for the vaccine rushed and went to get it asap. Now that most of the elderly are already vaccinated and the government is placing sanctions against people who are not vaccinated (can&#x27;t go shopping for clothes, can&#x27;t go to sport events, can&#x27;t go to the gym, can&#x27;t go to cultural events, etc...) the younger generation is much less anxious to get vaccinated. This is causing the vaccine centers stand mostly idle for the recent month.<p>The government and media in Israel have also started mentioning that they are anxiously waiting for Phizer to test the vaccines on children 12+yo and are preparing to vaccine children as soon as possible. Some speak out about vaccinating children even before the trials are complete.<p>At the same time, there is a little known &quot;cure&quot; that was developed in a Tel Aviv hospital that has been tried on 30 people who were in a severe condition due to covid. 29 of them went home after two days. All it took is a little bit of ventilation several times a day.
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