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CDC panel recommends resuming use of Johnson and Johnson vaccine

185 点作者 rafaelc大约 4 年前

13 条评论

nostromo大约 4 年前
Now maybe the US can finally approve the AstraZeneca vaccine and put our 20 million (!) doses on hand to good use.<p>Or not! But if we’re not going to use them, we should send them to another country like Canada or Mexico or Australia or the UK or EU, all of which have approved it and administered millions of doses.<p>Sitting on 10s of millions of vaccines during a pandemic is inexcusable.
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grej大约 4 年前
Both my wife and I got the J&amp;J shot before it was cancelled. We both had a period about 12 hours afterwards where we felt like we had a mild flu for about another 12 hours, then it was over and we’ve felt fine. Very happy with this decision.
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_wldu大约 4 年前
I had Covid in March 2020. It almost did me in. Was in ICU for a while.<p>Had the J&amp;J shot three weeks ago. Did not feel a thing. My arm was slightly sore at injection site. Nothing else. I guess my body was used to it and just sort of shrugged it off.<p>Some of my friends who got J&amp;J were sick for a few days, but rebounded quickly after that.
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joe_the_user大约 4 年前
Excellent news.<p>The unfortunate thing is the level of ignorance today mistakes a very careful effort make sure the vaccine is safe with a wanton ignoring of some danger.<p>Beyond talking about the fact that they determined this was safe, at some point educating people on danger in statistical terms is going to be necessary. But I&#x27;m not sure how that happens - addiction to headline-logic and single-heart-pulling-events is a huge part of the news industry.
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clarkevans大约 4 年前
J&amp;J is starting a 2-dose clinical study (<a href="https:&#x2F;&#x2F;clinicaltrials.gov&#x2F;ct2&#x2F;show&#x2F;NCT04614948" rel="nofollow">https:&#x2F;&#x2F;clinicaltrials.gov&#x2F;ct2&#x2F;show&#x2F;NCT04614948</a>), perhaps to see if it could have comparable effectiveness as the 2-dose mRNA Moderna and Pfizer protocols.<p>Unfortunately, the control arm for this study is a placabo instead of a single dose, which I would expect to be the standard of care.
LatteLazy大约 4 年前
I got confused as the same thing was reported in Oxford Astrozenica vaccine recipients. I wasn&#x27;t sure if they&#x27;re the same vaccine (they&#x27;re not). So I read up a bit.<p>The same sort of clots occur in people who have been given heparin (a blood thinner). It&#x27;s even called &quot;heparin induced&quot; in people using heparin.<p><a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Post-vaccination_embolic_and_thrombotic_events" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Post-vaccination_embolic_and_t...</a><p>People on either vaccine have been found to have an immune response to &quot;platelet factor 4&quot; (PF4). PF4s job is to moderate substances like heparin.<p>I wonder if PF4 is similar to spike protein somehow?<p>I wonder how long the immune response lasts?<p>I guess it&#x27;s not super useful as it wouldn&#x27;t make sense to give people a blood thickener (a coagulant?) prophylacticly. Maybe we need to consider whether this is appropriate for people on Heparin or similar medications? I&#x27;m no doctor so don&#x27;t take this as discouragment, I&#x27;m just musing. I have Oxford AZ (1 dose so far) and it was fine.
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jollybean大约 4 年前
This is great, but a gigantic Public Communications disaster.<p>I had a vax-sceptic friend send me an article from a reputable source, quoting claims from the National Health Agencies and WHO etc. about the &#x27;blood clots&#x27; which essentially conclude that &#x27;they are rare and treatable&#x27; ... but my friends &#x27;interpretation&#x27; was that the vax was &#x27;unsafe&#x27;. She literally couldn&#x27;t grasp that the data in the article was supposed to make her conclude it was &#x27;safe&#x27;. She just read &#x27;fear&#x27;.<p>40% of developed world people are either &#x27;not very literate&#x27; or &#x27;not paying attention&#x27; or have &#x27;reading comprehension&#x27; problems whereing they are not going to engage with the material to derive conclusions.<p>While the public health agencies decisions are a little cautious, they are reasonable, but the &#x27;communications&#x27; of it via random articles with bits of &#x27;facts&#x27; is a complete disaster from a Public Communications perspective and is causing probably measurable harm.<p>If there is a &#x27;marginal risk&#x27; of 4 in 1 million of &#x27;blood clotting&#x27; and it&#x27;s entirely treatable, then this information should be made available and transparent during the official conferences, but it should not be headline news.<p>Whenever material information is presented regarding concerns, they have to be contextualized, and if the conclusion is effectively &#x27;the vax is perfectly safe, this is just an administrative thing&#x27; then this has to be repeated over and over.<p>From the FDA: &quot;Out of every 10,000 women taking birth control pills, 3 to 9 of them will develop a blood clot&quot;.<p>That is about 100x greater than clotting from AstraZeneca Vaccine, and 10&#x27;s of millions of American women are taking it <i>daily</i>. Now that&#x27;s context.<p>Every single story about COVID needs to start and end with the &#x27;Net reality facts&#x27; about vaccination, which as of today is: &#x27;It&#x27;s utterly safe, basically for everyone, and it will help stop the spread and keep other safe&#x27;.<p>When messaging critical information for the masses it needs to be simple, clear, consistent, repetitive, words need to be chosen very carefully, and assume you&#x27;re dealing with a &#x27;Grade 8&#x27; audience in terms of net comprehension&#x2F;attention&#x2F;understanding.<p>Almost all intelligent professionals live in bubbles, we tend to have no grasp of how it is out there for a large swath of the population.<p>Even public health agencies web-sites are overloaded with information, literally with critical information in &#x27;downloadable PDFs&#x27; (???), it&#x27;s not good, I hope we develop a new approach but I don&#x27;t think we will.
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mancerayder大约 4 年前
Pausing like that causes, not prevents, vaccine skepticism. In an era of declining public trust of institutions (across both political aisles, even if unequally), I argue this pause was poor politics. Science doesn&#x27;t enter much into it, unfortunately.
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hn_throwaway_99大约 4 年前
I just read the linked Axios article, so perhaps there is more in the CDC decision, but seems like it would make the most sense to just recommend against the J&amp;J vaccine for anyone at higher risk of clot (e.g. all 6 of the people who had clots were women of childbearing age). With 3 good vaccines available, seems like there is plenty (or shortly will be plenty) to go around even if the J&amp;J vaccine only goes to those at low clot risk.
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sjm大约 4 年前
Just makes sense. The benefits far outweigh the risks at six cases of blood clots out of over 6.8 million doses, especially when there&#x27;s a high risk of blood clots following COVID-19 hospitalization. Not to mention rates of blood clots caused by the pill are more like 1 in 3000.<p>Hopefully if anything the pause has shown anti-vax folks that the safety of these vaccines is being taken seriously.
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passivate大约 4 年前
This is great news! I&#x27;m holding out for the J&amp;J shot myself :) I find it to be a better product than the others.
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ardit33大约 4 年前
Damage is done... NYC saw a drop in vaccine appointments right after the original ban on J&amp;J happen.<p>They could have issued a warning first, with the group ages&#x2F;sex that they were seeing the clots (it was mostly women). Now they are scaring the &#x27;indecisive&#x27; part of the population, and just making sure the pandemic will keep going.<p>Both the CDC and the FDA have completely dropped the ball during this pandemic. They are acting like typical bureaucrats, with the &#x27;you don&#x27;t fired if you buy IBM&#x27; type of mentality, and instead of being aggressive, they are just acting in a way so they don&#x27;t get fired.<p>They should have done challenge trials back in April last year, and ask for military style of mobilization on productions, instead of just doing the normal&#x2F;usual trails.<p>It would have speedup the vaccine rollout even more, and perhaps save at least 200k lives or more. (mask requirements on the Federal level, would have saved another 100-200k people).
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loceng大约 4 年前
In-depth talk with a virologist who believes that all of these vaccines currently be dangerous - and that we should perhaps stop all of them, please watch it before you assume you understand the reasoning:<p><a href="https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=BNyAovuUxro" rel="nofollow">https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=BNyAovuUxro</a> - DarkHorse Podcast with Geert Vanden Bossche &amp; Bret Weinstein
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