I flagged this. It's a perfectly fine paper, and quite interesting to someone with a deep interest in virology. However, the only purpose I can possibly see it serve in a Hacker News discussion is just to go around in circles on vaccine fears.<p>ADE is definitely one of the things to worry about, especially given that there were some signs in animal models and also in vitro. However, if ADE were an actual problem, we would be seeing <i>massive</i> signs of it, given how much virus is going around and how many people are vaccinated. That, of course, won't stop the "do your own research" people from freaking out.<p>ETA: Please, please prove me wrong. Post some comments that contribute towards an intellectually curious discussion. That will change my approach to this kind of thing. My cynicism is based on past patterns, but I don't think those are completely locked-in.