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Comparative Effectiveness of Moderna, Pfizer and J&J Vaccines

19 点作者 drocer88超过 3 年前

2 条评论

belter超过 3 年前
Are studies like this that make me loose respect for a part of the Medical community the CDC included. In the last few hours of course this study is already being quoted in the media.<p>The conclusions:<p>Vaccine effectiveness against COVID-19 hospitalization during March 11–August 15, 2021, was higher for the Moderna vaccine (93%) than the Pfizer-BioNTech vaccine (88%) and the Janssen vaccine (71%).<p>The critical point here folks, is &quot;during March 11–August 15&quot;<p>Their conclusion...<p>===========================================================<p>&quot;What are the implications for public health practice? &quot;Although these real-world data suggest some variation in levels of protection by vaccine, all FDA-approved or authorized COVID-19 vaccines provide substantial protection against COVID-19 hospitalization.&quot;<p>===========================================================<p>Part they forgot to mention....&quot;during March 11–August 15&quot;...<p>Also...They are measuring Vaccine Effectiveness not Efficacy<p>&quot;How do vaccine effectiveness studies differ from vaccine efficacy studies?&quot;<p><a href="https:&#x2F;&#x2F;www.cdc.gov&#x2F;flu&#x2F;vaccines-work&#x2F;effectivenessqa.htm" rel="nofollow">https:&#x2F;&#x2F;www.cdc.gov&#x2F;flu&#x2F;vaccines-work&#x2F;effectivenessqa.htm</a><p>And one of the critical differences is:<p>&quot;Vaccine effectiveness studies include people with underlying medical conditions who have been administered vaccines by different health care providers. Vaccine effectiveness studies can be used to determine if higher risk groups of people (often excluded from clinical trials&#x2F;RCTs) respond differently to the vaccine.&quot;<p>From the study they got 5484 and excluded 1786 patients for having immunocompromising conditions. Fine but that is about 32% of their universe...<p>Please remind me when and where these 32% of a certain population has been allowed to be excluded from current vaccine mandates?
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ekianjo超过 3 年前
So... J&amp;J&#x27;s vaccine is much less effective, but still &quot;fine to provide&quot;? It does not make any sense. If there&#x27;s a 20% gap between two different vaccines you should not use the less effective one unless you have a very good rationale to do so.
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