> The safety data break down like this: 425 out of 1029 patients, or 41.3%, on the 10mg/kg Aduhelm dose experienced ARIA. Serious cases cropped up in 14 of those patients, the JAMA analysis shows. ARIA-edema (ARIA-E), or swelling, was the most common side effect seen in the pooled data, affecting 362 patients, or some 35%. ARIA-microhemorrhage, also known as microbleed, and ARIA-superficial siderosis, which is a type of slow brain bleeding, was observed in 19.1% and 14.7% of patients, respectively.<p>> Ninety-four (26%) of the 362 patients with ARIA-E experienced symptoms, most commonly headache, confusion, dizziness and nausea, the analysis shows.<p>> Swelling or bleeding were mild to moderate in those patients, but scans did show severe side effects in 12.2% of patients with swelling, 11.7% in patients with microbleeds and 21.9% in patients with slow brain bleeding.