TE
科技回声
首页24小时热榜最新最佳问答展示工作
GitHubTwitter
首页

科技回声

基于 Next.js 构建的科技新闻平台,提供全球科技新闻和讨论内容。

GitHubTwitter

首页

首页最新最佳问答展示工作

资源链接

HackerNews API原版 HackerNewsNext.js

© 2025 科技回声. 版权所有。

Omicron extensively but incompletely escapes Pfizer vaccine neutralization

94 点作者 kareemm超过 3 年前

9 条评论

pigubrco超过 3 年前
Perhaps some good news from a paper out of Japan: <a href="https:&#x2F;&#x2F;twitter.com&#x2F;SystemsVirology&#x2F;status&#x2F;1474759694971727872?s=20" rel="nofollow">https:&#x2F;&#x2F;twitter.com&#x2F;SystemsVirology&#x2F;status&#x2F;14747596949717278...</a> &quot;The 6th preprint from G2P-Japan - #Omicron is less infectious and pathogenic than #Delta and even an early pandemic SARS-CoV-2 in infected hamster model.&quot;<p>Note: less infectious here means intra-cell, it&#x27;s still more transmissible than Delta.<p>Another thread summarizing what this means: <a href="https:&#x2F;&#x2F;twitter.com&#x2F;sailorrooscout&#x2F;status&#x2F;1475097966939721729" rel="nofollow">https:&#x2F;&#x2F;twitter.com&#x2F;sailorrooscout&#x2F;status&#x2F;147509796693972172...</a>
评论 #29698576 未加载
评论 #29698806 未加载
评论 #29703507 未加载
blhack超过 3 年前
Is there any evidence that shows that omicron is even particularly dangerous?<p>There has a been a “savior” strain that a lot of us have been hoping for which is: extremely transmissible, and relatively benign. So far it seems like omicron could be that, but I haven’t actually seen good data on mortality yet.<p>If anybody has good mortality data I would love to see it.
评论 #29698973 未加载
评论 #29699234 未加载
评论 #29698999 未加载
评论 #29699213 未加载
评论 #29703602 未加载
评论 #29699062 未加载
评论 #29698948 未加载
评论 #29699298 未加载
评论 #29698877 未加载
armchairhacker超过 3 年前
This is completely untested but i would assume that the more times you get infected or vaccinated, the more resistance you get to subsequent infections. The alternative is that covid variants keep reinfecting people over and over and people who just barely make it out of the hospital come back, which is <i>really</i> bleak.<p>So Omicron is reinfecting people but it’s not as severe, not only because of specific mutations, but because most people have already been infected &#x2F; vaccinated multiple times.<p>This would also apply to other diseases. So if someone has been infected with e.g. the flu 5 times, it debunks this theory. IIRC there are multiple common colds which would explain why some people get sick with cold almost every year (and even then infections tend to be spread out). Anecdotally there was one time i was infected with some sort of stomach bug 4 times in a short span, but i’ve never had a stomach bug since then.
ck2超过 3 年前
Not just pfizer, everything, MABS and including previous infection too<p><a href="https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;d41586-021-03796-6" rel="nofollow">https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;d41586-021-03796-6</a><p><a href="https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;d41586-021-03826-3" rel="nofollow">https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;d41586-021-03826-3</a><p><a href="https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2021.12.22.21268021" rel="nofollow">https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2021.12.22.21268021</a><p>The question is if you get omicron can you then turn around and get delta which is still out there, just being out-competed at the moment.
评论 #29699001 未加载
评论 #29698492 未加载
aix1超过 3 年前
Could anyone explain the significance of this finding?
评论 #29698499 未加载
评论 #29698394 未加载
评论 #29698425 未加载
评论 #29698550 未加载
userbinator超过 3 年前
I wonder how Moderna compares --- besides the higher does, the mRNA is a slightly different sequence.
_v7gu超过 3 年前
Recommendation of boosters is short-sighted and is only valid while this variant is active. Give vaccines to Africa instead so there will be no new variants. A first dose is much more valuable than a third
评论 #29699318 未加载
评论 #29700294 未加载
评论 #29699534 未加载
keyle超过 3 年前
Are they specifically trying to use confusing English?!
tiahura超过 3 年前
<a href="https:&#x2F;&#x2F;ourworldindata.org&#x2F;mortality-risk-covid" rel="nofollow">https:&#x2F;&#x2F;ourworldindata.org&#x2F;mortality-risk-covid</a><p>It would appear that mass vaccination had a minimal effect on the already low case fatality rate. I think it’s getting harder and harder to justify lockdowns and forced masking.
评论 #29699036 未加载
评论 #29698873 未加载
评论 #29698757 未加载
评论 #29698780 未加载