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Likely cause of mystery child hepatitis outbreak found

100 点作者 iamben将近 3 年前

18 条评论

jl6将近 3 年前
I hope that the legacy of covid lockdowns is a renewed appreciation for the second-order, systemic, and unintended consequences of any action, to be weighed against the direct and intended effects.
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amluto将近 3 年前
I think this is the actual paper: <a href="https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2022.07.19.22277425v1" rel="nofollow">https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2022.07.19.22277425v...</a><p>And be careful before attributing this to COVID lockdowns. In the US, at least, there does not actually appear to have been any meaningful increase in hepatitis in young children:<p><a href="https:&#x2F;&#x2F;www.cdc.gov&#x2F;mmwr&#x2F;volumes&#x2F;71&#x2F;wr&#x2F;mm7124e1.htm" rel="nofollow">https:&#x2F;&#x2F;www.cdc.gov&#x2F;mmwr&#x2F;volumes&#x2F;71&#x2F;wr&#x2F;mm7124e1.htm</a><p>The UK could be different for any number of reasons, but, at least in the actual paper and in the US, this does not appear to be COVID-related, even indirectly.
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sylware将近 3 年前
I don&#x27;t understand why a slightly delayed exposure to some &quot;common&quot; viruses can almost destroy the liver of young children.
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iamben将近 3 年前
The Glasgow University post: <a href="https:&#x2F;&#x2F;www.gla.ac.uk&#x2F;news&#x2F;headline_863600_en.html" rel="nofollow">https:&#x2F;&#x2F;www.gla.ac.uk&#x2F;news&#x2F;headline_863600_en.html</a>
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trention将近 3 年前
This is a hypothesis based on a sample size of 9 and already in the comments people are treating it like gospel while pushing their political agendas.<p>Humanity is really (mostly) unfit to deal with both nuanced information and collective action problems.
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jagged-chisel将近 3 年前
&gt; The two teams of researchers, from London and Glasgow, say infants exposed later than normal - because of Covid restrictions - missed out on some early immunity to:<p>&gt; - adenovirus, which normally causes colds and stomach upsets<p>&gt; - adeno-associated virus two, which normally causes no illness and requires a coinfecting &quot;helper&quot; virus - such as adenovirus - to replicate<p>&gt; That could explain why some developed the unusual and worrying liver complications.
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BaculumMeumEst将近 3 年前
This is going to terrify people just like stories about infant mortality from COVID terrified people. But the article is talking about infections of 1,000 children across <i>35 countries</i>. These stories shooting to the front page over and over is giving a distorted view of reality that didn’t exist before social media.
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woliveirajr将近 3 年前
Remembers me about Acute Lymphoblastic Leukemia (ALL):<p>&gt; Epidemiologic studies indicate that infections in early childhood may protect against pediatric acute lymphoblastic leukemia (ALL)... our results support Greaves’ hypothesis that delayed exposure to infections in early childhood increases risk of ALL. [1]<p>[1] <a href="https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC4100471&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC4100471&#x2F;</a>
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willmadden将近 3 年前
That&#x27;s a junk article based on a garbage paper making wild speculative claims that lockdowns prevented kids from exposure to cold viruses, somehow resulting in colds giving kids hepatitis.<p>If you read the full text of the paper here: <a href="https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2022.07.19.22277425v1.full" rel="nofollow">https:&#x2F;&#x2F;www.medrxiv.org&#x2F;content&#x2F;10.1101&#x2F;2022.07.19.22277425v...</a> you&#x27;ll see their sample size was insufficient and cherry picked. They only looked at nine (9) cases and fifty eight (58) control subjects. Furthermore, they don&#x27;t specify their sampling criteria, but they do mention they did NOT include children that were vaccinated in the study. Why?<p>What we do know is that there is emerging evidence that both COVID and COVID vaccination dysregulate the immune system, allowing diseases (like shingles) that are normally suppressed by the immune system until later in life to suddenly appear in young people.<p>Scotland started their child vaccination program in January 2022, around three (3) months in advance of the &quot;worldwide hepatitis outbreak&quot;: <a href="https:&#x2F;&#x2F;web.archive.org&#x2F;web&#x2F;20220124104228&#x2F;https:&#x2F;&#x2F;www.nhsinform.scot&#x2F;covid-19-vaccine&#x2F;the-vaccines&#x2F;vaccinating-children-aged-5-to-11-years&#x2F;" rel="nofollow">https:&#x2F;&#x2F;web.archive.org&#x2F;web&#x2F;20220124104228&#x2F;https:&#x2F;&#x2F;www.nhsin...</a><p>They need to redo the research, but use a much larger RANDOM sampling of all children who came down with hepatitis, and look for correlations with both COVID infection and COVID vaccination against hepatitis infection.<p>My educated guess is that it had little to do with lockdowns, and much more to do with immune system dysregulation from both COVID and COVID vaccination.
sudden_dystopia将近 3 年前
The path to hell is paved with good intentions.
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nikolay将近 3 年前
Nothing new under the sun - the Hygiene Hypothesis [0] at play!<p>[0]: <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Hygiene_hypothesis" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Hygiene_hypothesis</a>
ed25519FUUU将近 3 年前
The cause seems to be social distancing preventing necessary exposure to two types of adenovirus.<p>Sounds like another 2nd-order effect from lockdowns that has been disproportionately harder on children than adults. Really glad I moved out of my “pro lockdown” state.
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TheBlight将近 3 年前
This feels like half of the answer.
bediger4000将近 3 年前
&gt; Scientists have ruled out any connection with coronavirus or Covid vaccines.<p>Well, that&#x27;s a relief.
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dfbsdfbwe2ef2e将近 3 年前
Isn&#x27;t the _actual_ problem here the fact that these kids weren&#x27;t vaccinated against hepatitis?
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nikolay将近 3 年前
Should this be categorized as Hepatitis D and require an adenovirus vaccine then?
CodeWriter23将近 3 年前
I had no idea the adenovirus vaccine provided immunity to hepatitis.
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yonaguska将近 3 年前
Scientists and doctors that warned about the health costs of lockdowns on children were cancelled. We really need to set up a Ministry of Ministry of Truth. &#x2F;s<p>On a serious note, can we ask how we got here? Why were lockdowns so unquestionably pushed?<p>&gt; No sooner had we convinced the Trump administration to implement our version of a two-week shutdown than I was trying to figure out how to extend it. Fifteen Days to Slow the Spread was a start, but I knew it would be just that. I didn’t have the numbers in front of me yet to make the case for extending it longer, but I had two weeks to get them. However hard it had been to get the fifteen-day shutdown approved, getting another one would be more difficult by many orders of magnitude.<p>Dr Birx from her book.<p>But she&#x27;s far from the only one to blame.
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