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Nearly half of Covid patients haven’t fully recovered months later, study finds

105 点作者 lxm超过 2 年前

27 条评论

300bps超过 2 年前
<a href="https:&#x2F;&#x2F;archive.ph&#x2F;eLXeH" rel="nofollow">https:&#x2F;&#x2F;archive.ph&#x2F;eLXeH</a>
dmix超过 2 年前
I&#x27;m curious if this study refutes or supports this often cited study on long COVID (I can&#x27;t tell from the NYTimes article):<p>&gt; We demonstrate an absence of association between symptom burden and radiographic or biochemical abnormality. We suggest that the phenomenon of Long-COVID may not be directly attributable to the effect of SARS-CoV-2, but rather the neuropsychiatric insults may play a greater role in its aetiology.<p>There was a similar phenomenon after 9-11 and gulf war:<p>&gt; Similar post-traumatic syndromes, such as Gulf War Illness and post-9&#x2F;11 syndrome, describe the occurrence of both physical and psychological symptoms in a similar pattern to what is being observed in Long-COVID.<p><a href="https:&#x2F;&#x2F;sci-hub.st&#x2F;https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;33569660&#x2F;" rel="nofollow">https:&#x2F;&#x2F;sci-hub.st&#x2F;https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;33569660&#x2F;</a><p>&quot;Breathlessness, palpitations and confusion or difficulty concentrating&quot; seem to be the primary symptoms according to NYTimes but I&#x27;m curious if they&#x27;ve found any &#x27;radiographic or biochemical abnormality&#x27; in this case... or whether that even matters. COVID was obviously a very serious and traumatic occurrence, especially for people who got a severe case.
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timr超过 2 年前
Here is the link to the actual study:<p><a href="https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41467-022-33415-5" rel="nofollow">https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41467-022-33415-5</a><p>One thing that immediately leaps out to me is that the profile of &quot;symptoms&quot; is broadly similar between &quot;never infected&quot; and &quot;symptomatic infected&quot; groups, but <i>completely different</i> (much lower across the board) for &quot;asymptomatic infected&quot;:<p><a href="https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41467-022-33415-5&#x2F;tables&#x2F;2" rel="nofollow">https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41467-022-33415-5&#x2F;tables&#x2F;2</a><p>There does seem to be elevation vs. controls for certain symptoms (including a few that are mechanistically believable, such as shortness of breath), but because this is <i>self-reported data</i>, it&#x27;s still hopelessly biased. People who self-identify as sick are going to be more likely to report symptoms than those who do not...which is probably why we see the much lower rates of &quot;long covid&quot; symptoms in the asymptomatic infection group.<p>At the very least, this should make you question the idea of &quot;long covid&quot; after asymptomatic infection. Based on this data, &quot;long covid&quot; is closer to the symptom profile seen in people who were <i>never infected at all</i> than it is to the symptom profile of people who knew they were infected, but didn&#x27;t have primary illness.
sdrothrock超过 2 年前
Some anecdata... (two doses of Moderna, still haven&#x27;t gotten the third shot available here and that&#x27;s on me for not making time)<p>Got covid in the spring, lost my sense of taste, but it started gradually coming back after about six months.<p>Got it again a month ago, lost my senses of smell and taste, also have a persistent cough, persistent tinnitus, tiredness, and more frequent migraines.
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readthenotes1超过 2 年前
I know 21 people that have had covid, from 3 to 91. 1 person had long covid, still requires oxygen months later.<p>Either my friends and family are unduly healthy, or there&#x27;s maybe something questionable about the &quot;half&quot;.<p>If I flipped a coin 21 times and it only came up tails once, I wouldn&#x27;t believe it was a fair coin...
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nvahalik超过 2 年前
Anecdata: I&#x27;ve had Covid once. Whole family got it. Going out for walks was not impossible but winded me badly. We all recovered in about a week.<p>I had a single dose of Pfizer from about 3 months before. I never got a second dose. Kids all breezed through it.<p>The first month afterward required a lot of pushing and experimenting to get my body to respond to working out. Stuff like walking for extended periods of time was easy, but anything that got my HR into Zone 3 and above was taxing. After that month, things got progressively easier.<p>I also made a lot of other changes: diet improved tremendously, I lost 30+ pounds, and I feel like a completely different person now than before.<p>The only other people I know personally who got long covid had gotten 2 doses but had other issues like being overweight or having a horrible diet.
uptownfunk超过 2 年前
This disease has completely changed the state of life for everyday America. I used to be able to run easily for miles. Since COVID I can barely get out a few miles a week.
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didgetmaster超过 2 年前
Never got tested, but my senses of taste and smell changed dramatically about 6 months ago. No other symptoms whatsoever. Everything tastes &#x27;funny&#x27; like there it is contaminated with a drop of motor oil or something. Lost about 15 pounds just because I don&#x27;t particularly feel like eating because it just isn&#x27;t enjoyable. I usually love the garden tomatoes this time of year, but not this year. I have noticed that it has improved some, but I&#x27;m not sure if I am just getting used to it.
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John23832超过 2 年前
I caught OG covid in June of 2020. I&#x27;ve had it once more (Feb of this year). Exposed a third time but tested negative (who knows about these tests). I&#x27;ve had fatigue, tinnitus, and a persistent neck pain since the Feb infection. What I would consider neurological symptoms as well (extremity weakness, vertigo, headaches). I&#x27;m pretty young (31). Prior to Feb, I was pretty active. Weight lifting every day, running 2 miles every other. Now, the fatigue and weakness really has gotten the best of me. The neck pain and tinnitus is something I can deal with though. I&#x27;ve had multiple tests (cats and mris)... nothing remarkable.<p>Probably long covid.
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lend000超过 2 年前
Anecdata: I had what seemed like relatively mild covid in March 2020, but never fully recovered, and I ended up unable to do strenuous or stressful activity without a super fight or flight physical response. I was in my 20&#x27;s, and originally very active and fit, although I ate a very high sugar&#x2F;carb diet.<p>I took a lot of tests and tried a lot of things and made no progress with doctors for about 2 years, until I tried doing a more aggressive version of the paleo diet (even avoiding most fruits), and now I&#x27;m making significant progress, slowly ramping up my workouts and the amount of stress my body can take. I&#x27;m also taking supplements like Zinc and some Asian herbs that are intended to raise testosterone, which I understand to reduce cortisol&#x2F;the stress response. I&#x27;m also meditating most days and taking a cold shower daily. I think the diet is the biggest factor though -- whenever I accidentally eat a high-GI meal, I feel the symptoms hit immediately.
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benhoyt超过 2 年前
Seeing people are sharing stories ... I&#x27;m a pretty healthy 41-year old, I live in New Zealand, got two Pfizer shots in late 2021, then got Covid in April 2022. It was like a bad flu, but I recovered from the main symptoms after a week or so, and felt drained for another few weeks. So far so good.<p>But ever since recovering from Covid I&#x27;ve had this tightness&#x2F;squirming feeling around my stomach&#x2F;gut at night, and it really hinders my sleep. I&#x27;ve been to the doctor several times. Nothing&#x27;s wrong with my heart, and nothing major with my gut either; he can&#x27;t figure out what it is. At this point I&#x27;m starting to wonder whether it&#x27;s psychosomatic, though I&#x27;m not an anxious person, and wasn&#x27;t terribly worried about Covid. The timing definitely coincides with my recovery from Covid. I&#x27;m hoping it just goes away eventually...
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JohnTHaller超过 2 年前
I&#x27;m an example here. Still have a mostly-broken sense of smell 2.5 years later. My neighbor is on beta blockers in his 30s thanks to Covid.
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NaturalPhallacy超过 2 年前
Probably because they haven&#x27;t recovered from being obese. Obesity is second only to smoking in terms of bad for your health.<p>73% of Americans are overweight or obese.
NDizzle超过 2 年前
Alpha ran through my family of 5 around Christmas time, 2020. We were down 4-6 days, that was it.<p>Everyone operating normally since then, my kids play a lot of sports at a high level. I coach, exercise, etc, while not in my best shape ever, it’s mostly cause of limited time.<p>No vaccines, won’t ever get them.
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ekianjo超过 2 年前
Anecdotal evidence but after catching covid and having residual symptoms I found that taking Zinc actually worked well to alleviate them. Ymmv but worth trying if you are struggling.
spike021超过 2 年前
I can&#x27;t confirm this but I _may_ have had COVID Jan 2020, and ever since then I get waves of coughs &#x2F; other symptoms every couple weeks or so that last for at least a week; it never goes away.<p>Never had anything like this before that one time being sick other than seasonal bronchitis a few years in a row about a decade ago.<p>Only other thing I can thing of is allergies but I&#x27;ve now lived in multiple places during the past 2 years, visited different areas, and it still recurs.
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baskethead超过 2 年前
I&#x27;ve had 3 shots of Moderna and got my first infection of COVID 3 weeks later. I&#x27;ve had COVID 2 more times after that, the most recent being about a month ago.<p>The first two times were sore throat with congestion. The last time was sore throat with congestion and sore joints for a day with fever. All symptoms except for congestion lasted for a day, and congestion lasted for a week. Annoying but nothing more than a bad cold for me.
achairapart超过 2 年前
I wonder if this may apply to Omicron too. I just got Covid, symptoms started 2 days ago but as of today I already feel almost fully recovered.
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lamontcg超过 2 年前
&gt; Overall, 102,473 (16%) of the 638,125 people invited consented and completed at least one questionnaire: 33,281 (20%) of the 162,957 people who had a positive test, and 69,192 (15%) of the 475,168 invited following only negative tests.<p>That still looks like a pretty poor response rate.
woopwoop24超过 2 年前
male 34, had it nov 2020, symptoms started dez&#x2F;jan 2021. still chest pain, nausea, unrefreshing sleep and weird heart palpations and high pulse. got better over time, i am hoping the will release bc007 soonish, so that might be a solution for all of us struggling with our lives and wanting a normal life back. extremely frustrating knowing what was possible and not able to reach that again still happy to hear that most of the people recover just fine.
Markoff超过 2 年前
Not fully recovered = people with mental issues<p>&gt; People with previous symptomatic Covid infections reported certain persistent symptoms, such as breathlessness, palpitations and _confusion_ or _difficulty concentrating_, at a rate roughly three times as high as uninfected people in surveys from six to 18 months later, the study found.<p>Also:<p>&gt; Women, older people and those living in poorer areas also faced more serious aftereffects from an infection.<p>TLDR people more likely to be depressed were find to be depressed and someone tries to claim it&#x27;s thanks to COVID infection. &#x2F;facepalm
jdkee超过 2 年前
&quot;Only a small portion of the study participants — about 4 percent — had been vaccinated before their infections, and many of those with only a single dose.&quot;<p>Strong argument for the protective nature of the COVID vaccines. Although the virus certainly appears less damaging now in 2022 as opposed to when it first appeared.
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entropicgravity超过 2 年前
Are we in a pandemic of chronic fatigue symptom (CFS)?
WirelessGigabit超过 2 年前
1 year later. Still deafening tinnitus in left ear.
sumosudo超过 2 年前
Can anybody tell me what the official clinical diagnosis of covid-19 is?
mancerayder超过 2 年前
I had covid 6 months ago and it lasted 2.5 months.<p>But it was partially psychological: whether that partial was 10% or 50% or 80%, you can judge.<p>The acute phase lasted two weeks. I had a very strong mix of what was a bad cold and allergy symptoms, progressing to a dry cough from a very bad wet cough. I also had dizziness, forgetfulness, and at one point everything in the world smelled of orange for a week. I had terrible, terrible health care, I was given steroids that spiked my resting heart rate to 110-120 (normally 55-60), told nonsense advice ranging from &quot;it&#x27;s just a cold&quot; to &quot;here&#x27;s a Z-PAC in case it gets worse&quot; (I never took it), and of course I never qualified for the antivirals for reasons best left not mentioned here without causing a political argument, the part that makes me the angriest of all.<p>Anyway, after that for two months I had shortness of breath, strange sleep issues, dizziness, and chest tightness. I went to see a lung specialist in a long covid specialty part of a famous hospital chain in the first two weeks of that period. I was told I was at risk for mitochondrial dysfunction, that I should never do strength training again, that some of the other patients became crippled after one year. That POTS was a risk, etc. That athletes have the highest risk for permanent disablement from long covid.<p>I became distraught, and during this time had some of the darkest thoughts of my life. Can&#x27;t exercise? Risk for POTS? Disabled? That&#x27;s it for me. I had dark circles under my eyes and fell into a sort of depression. Dysautonomia is the generalized name for the disorder. Anxiety was triggered, and it played its role.<p>I remember I&#x27;d taken an Uber at one point who told me that the vaccine gave him symptoms, and he described all the same stuff as me: shortness of breath, waking up at night sweating randomly, dizziness. He was wide-eyed as I explained long covid &#x2F; dysautonomia. He had had covid prior to the vaccine, and I told him that was the cause.<p>Then one day I went back to the specialist and I brought with me a printout of an endoscopy I&#x27;d done a few months prior that showed esophageal inflammation and a GERD diagnosis. I also had a detailed printout of exercise attempts, and notes and dates for what I experienced that night, the next day and the day after, rating the shortness of breath, sleep disturbances, etc. I did a stress test with a cardiologist that showed I was exceeding the markers at every level, was cleared. After that both cleared me for exercise.<p>Overnight my mood change, my physical body felt more healed, and I went full speed ahead in revamping my exercise regimen.<p>Literally everything was fine, then.<p>Well. This weekend I was exposed to covid and today, day 4, I&#x27;m testing negative but experiencing some cold symptoms and some chest congestion.<p>How much of the above is in my head versus actual is open to debate. I honestly don&#x27;t know the answer.<p>But sometimes I wonder, if no one ever told me anything about covid, and ignorance were bliss, how much healthier I&#x27;d probably be and how much better the last six months would have been!
classichasclass超过 2 年前
My wife took three months to recover. I have a friend roughly my age who still hasn&#x27;t (about four months in). My dad is dead.<p>And people wonder why I don&#x27;t blow it off. I&#x27;ve yet to get it, and I don&#x27;t want to.
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