They have encountered an interesting algorithmic problem here, very cool.<p><pre><code> To determine whether the universe as a whole has a preferred handedness, they had to repeat the analysis for all tetrahedra constructed from their database of 1 million galaxies. There are nearly 1 trillion trillion such tetrahedra — an intractable list to handle one at a time. But a factoring trick developed in earlier work on a different problem allowed the researchers to look at the parity of tetrahedra more holistically: Rather than assembling one tetrahedron at a time and determining its parity, they could take each galaxy in turn and group all other galaxies according to their distances from that galaxy, creating layers like the layers of an onion.
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The linked earlier work: <a href="https://academic.oup.com/mnras/article/454/4/4142/993302" rel="nofollow">https://academic.oup.com/mnras/article/454/4/4142/993302</a>