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Intermittent fasting may negate need for diabetes drugs, small study suggests

43 点作者 supermatou超过 2 年前

6 条评论

Johnny555超过 2 年前
That&#x27;s a pretty long fasting interval:<p><i>&quot;is a new proposed dietary approach based on [intermittent fasting] involving five fasting days followed by 10 days of reintroducing everyday food items.&quot;</i><p>And when they say &quot;everyday food items&quot; they apparently mean a special diet:<p><i>The diet contains daily foods such as wheat, barley, rice, rye and oat, &quot;and features reduced glycemic loads, calories, and carbohydrates, as well as increased unsaturated fatty acids,&quot; the scientists said.</i><p>It doesn&#x27;t appear that they tested a group that had the special diet but without the intermittent fasting.
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hwayne超过 2 年前
I was skeptical and did some further reading, but it seems like there&#x27;s other papers showing that diabetes is reversible with weightloss. In particular:<p>- This 2006 paper found that bariatric surgery can reverse diabetes: [2006]<p>- This paper reversed diabetes in people purely through calorie restriction: [2011]<p>- This survey article [2020] finds that about half (!) of diabetics who lose 15 kg totally reverse type 2, and no longer need any medication. It also proposes mechanisms for why this works.<p>I&#x27;m not a doctor or a medical researcher and don&#x27;t have the skill to read these studies carefully. But it seems that it&#x27;s generally known now that diabetes is reversible with dieting? Of note the 2020 article is a little stricter than TFA: it says that the HbA_1c threshold has to below 6.5% even after <i>six</i> months of no medication, while TFA defines it as <i>three</i> months. Given that the &quot;only 2.8% of control group individuals achieved remission&quot;, it&#x27;s possible that intermittent fasting only helped vis-a-vis weight loss, and as long as you lose enough weight you can potentially reverse diabetes.<p>It&#x27;d be nice if TFA was on sci-hub.<p>[2006] <a href="https:&#x2F;&#x2F;diabetesjournals.org&#x2F;diabetes&#x2F;article&#x2F;55&#x2F;7&#x2F;2025&#x2F;14198&#x2F;Mechanisms-of-Recovery-From-Type-2-Diabetes-After" rel="nofollow">https:&#x2F;&#x2F;diabetesjournals.org&#x2F;diabetes&#x2F;article&#x2F;55&#x2F;7&#x2F;2025&#x2F;1419...</a><p>[2011] <a href="https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;21656330&#x2F;" rel="nofollow">https:&#x2F;&#x2F;pubmed.ncbi.nlm.nih.gov&#x2F;21656330&#x2F;</a><p>[2020] <a href="https:&#x2F;&#x2F;www.bmj.com&#x2F;content&#x2F;374&#x2F;bmj.n1449" rel="nofollow">https:&#x2F;&#x2F;www.bmj.com&#x2F;content&#x2F;374&#x2F;bmj.n1449</a>
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diabeetusman超过 2 年前
I&#x27;m not seeing the reasoning behind intermittent fasting in particular as opposed to losing weight in general. Couldn&#x27;t the title just have equivalently been &quot;losing weight may negate need for [type 2] diabetes drugs&quot;?
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teilo超过 2 年前
It just astounds me that they still insist on a diet of grains and other carbs for type-2 diabetes.
chrispeel超过 2 年前
There&#x27;s a big difference between type 1 and type 2 diabetes; this study focuses on type 2. It would be better if the HN title and the title on upi.com included &quot;type 2&quot;.
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smitty1e超过 2 年前
I go breakfast-to-breakfast several times a month.<p>Feels great.<p>Little weight loss value, but still.