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Visualizing the inside of cells at previously impossible resolutions

34 点作者 cheinyeanlim超过 2 年前

6 条评论

lordfrito超过 2 年前
If you&#x27;re interested in seeing images generated by this technique, a google image search of &quot;Cryo-Electron Tomography&quot; came up with tons of hits.<p>Here&#x27;s a sample of articles with images [1] [2] [3]<p>Wild stuff. I never would have guessed that we&#x27;d be able to image intact cell biology at this resolution in my lifetime. Excited for the possibilities for new discoveries opened up with all these new tools&#x2F;methods.<p>[1] <a href="https:&#x2F;&#x2F;www.thermofisher.com&#x2F;blog&#x2F;atomic-resolution&#x2F;whats-possible-cryo-electron-tomography&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.thermofisher.com&#x2F;blog&#x2F;atomic-resolution&#x2F;whats-po...</a><p>[2] <a href="https:&#x2F;&#x2F;www.biorxiv.org&#x2F;content&#x2F;10.1101&#x2F;2021.07.28.454169v1.full" rel="nofollow">https:&#x2F;&#x2F;www.biorxiv.org&#x2F;content&#x2F;10.1101&#x2F;2021.07.28.454169v1....</a><p>[3] <a href="https:&#x2F;&#x2F;www.biochem.mpg.de&#x2F;5268912&#x2F;20160226_Mahamid_Baumeister" rel="nofollow">https:&#x2F;&#x2F;www.biochem.mpg.de&#x2F;5268912&#x2F;20160226_Mahamid_Baumeist...</a>
s1artibartfast超过 2 年前
Article: <a href="https:&#x2F;&#x2F;febs.onlinelibrary.wiley.com&#x2F;doi&#x2F;10.1002&#x2F;1873-3468.13948" rel="nofollow">https:&#x2F;&#x2F;febs.onlinelibrary.wiley.com&#x2F;doi&#x2F;10.1002&#x2F;1873-3468.1...</a>
schemescape超过 2 年前
Are there images somewhere in the article?<p>All I saw was a title image (not sure if it is real or just an artistic interpretation), and a video (with a thumbnail that looked interesting, but apparently just a bunch of people talking).
hoseja超过 2 年前
&gt;Samples are rapidly frozen to protect them from radiation damage.<p>Isn&#x27;t this wrong? They are rapidly frozen so the water vitrifies and permits transmission of the electron beam. The samples still get damaged by the what is basically beta radiation.
veilrap超过 2 年前
For a moment I thought this article was going to be about doing visualizations of cells using Vi(m)
评论 #34322956 未加载
maroonblazer超过 2 年前
vid Insights Into How They Work