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Ask HN: Is Wikipedia's antidepressant page objective?

6 点作者 sirobg将近 2 年前
<a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Antidepressant" rel="nofollow noreferrer">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Antidepressant</a><p>The page contains several positive sentences about antidepressants. 3 random examples:<p>- Reviews of antidepressants generally find that they benefit adults with depression.<p>- For children and adolescents, fluvoxamine is effective in treating a range of anxiety disorders. Fluoxetine, sertraline, and paroxetine can also help with managing various forms of anxiety in children and adolescents.<p>- Unlike social anxiety and PTSD, some TCAs antidepressants, like clomipramine and imipramine, have shown efficacy for panic disorder.<p>But most of the page feels doubtful, or even against the use of these drugs.<p>For example, the introduction is really scary in itself. You can read that:<p>- There is an increased risk of suicidal thinking and behavior when taken by children, adolescents, and young adults.<p>- Other researchers also conclude that anti-depressants ultimately do more harm than good, indicating that they cause permanent neuronal damage, apoptosis and disrupt numerous adaptive processes regulated by serotonin.<p>- The placebo effect may account for most or all of the drugs&#x27; observed efficacy<p>And all these points are really poorly counterbalanced.<p>I think one could argue the page tends to discourage the take of antidepressants.<p>But still, doctors all over the world are prescribing them.<p>Is Wikipedia accurate here?<p>If so, why are doctors prescribing them? I heard a lot of takes gravitating around: &quot;pharmaceutical industry makes a lot of money with them, so they push the use of these drugs&quot;, but it seems to conspiracy-theory-ish to be true.<p>Is Wikipedia inaccurate here?<p>If so, why? Can we trust Wikipedia objectivity?

4 条评论

nullindividual将近 2 年前
&gt; Is Wikipedia accurate here?<p>SSRIs are a crapshoot (&lt;50% respond). I don&#x27;t know if&#x2F;how the industry pushes them (they&#x27;re cheap, no one &#x27;pushes&#x27; generics).<p>Nothing you quoted is incorrect, with possibly the exception of:<p>- Reviews of antidepressants generally find that they benefit adults with depression.<p>SSRIs have more recently been shown to be less effective than previously thought.<p><a href="https:&#x2F;&#x2F;www.nytimes.com&#x2F;2022&#x2F;04&#x2F;21&#x2F;well&#x2F;antidepressants-ssri-effectiveness.html" rel="nofollow noreferrer">https:&#x2F;&#x2F;www.nytimes.com&#x2F;2022&#x2F;04&#x2F;21&#x2F;well&#x2F;antidepressants-ssri...</a><p>&gt; over the course of two years, the changes in quality of life reported by Americans with depression who took antidepressants versus the changes reported by those with the same diagnosis who did not take the medications.<p>&gt; The paper found no significant differences in the changes in quality of life reported by the two groups, which suggests that antidepressant drugs may not improve long-term quality of life.<p>SSRIs can also activate Bipolar disorder.
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ambyra将近 2 年前
I don’t think Wikipedia should be used to steer a decision. It just aggregates information on a topic.<p>Regarding drug use, it’s up to the parents. If the parents are unable to tolerate their child’s behavior, they’re more likely to accept giving their child drugs. If they’re on drugs themselves, they’ll be more likely to give them to their child. If they’re more “hands off” they’re more likely.<p>Is it better to have a wild, moody, potentially suicidal child or a baked potato? Some parents prefer the baked potato.
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i8comments将近 2 年前
Wikipedia is generally neutral and objective.<p>Are you asking if antidepressants are good or if you should take them? Ask a doctor.
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andsoitis将近 2 年前
What do health organizations, like the NIH, AMA, and APA (or other, non-American organizations) have to say about antidepressants?<p>Similar to Wikipedia or divergent?
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