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Biohacking Lite (2020)

184 点作者 daco超过 1 年前

22 条评论

spondylosaurus超过 1 年前
&gt; A human body is like an iPhone with a battery pack that can grow nearly indefinitely, and with the abundance of food around us we scarcely unplug from the charging outlet. In this case, the batteries are primarily the adipose tissue and triglycerides (fat) stored within, which are eagerly stockpiled (or sometimes also synthesized!) by your body to be burned for energy in case food becomes scarce.<p>Incidentally, this is how&#x2F;why liposuction works: if you remove fat cells from a certain area, your body can&#x27;t store fat in that spot anymore. The flip side being that if you gain weight afterwards, it still has to go <i>somewhere,</i> but you can&#x27;t&#x2F;won&#x27;t store fat in the lipo&#x27;d spot.<p>And you can&#x27;t remove every single fat cell in your body because you do need to store fat to stay alive, but it&#x27;s good for sculpting specific areas.<p>(I should add that I got a bit of lipo done ~6 months ago and I&#x27;m loving it so far. Very little in the way of pounds shed, but it made a huge difference for my silhouette, which is what I wanted.)
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carlsborg超过 1 年前
The Mifflin-St Jeor equation equation for working out Base Metabolic Rate, as stated in this post, is for males. The original subtracts a different constant for females (-161 instead of -5). It is a 1990 paper. And it subtracts these arbitrary constants independent of the other variables, makes me think its limited in its usefulness.<p>I believe that weight training, maybe even cardio, increases this BMR for many hours after the workout, so I dont agree with the &quot;not a major contributor to losing weight&quot; argument if its done regularly.
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tpush超过 1 年前
&gt; Avoid sugar like the plague, including carbohydrate-heavy foods that immediately break down to sugar (bread, rice, pasta, potatoes), including to a lesser extent natural sugar (apples, bananas, pears, etc - we’ve “weaponized” these fruits in the last few hundred years via strong artificial selection into actual candy bars), berries are ~okay.<p>This is not an evidence-based approach. I swear all these nutrition grifter folks on YouTube and Twitter melted certain people&#x27;s brain.
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timzaman超过 1 年前
I recall andrej walking around the office at this time (tesla), bad-mouthing all the sugar products that came into his view, claiming they are weaponized; and very pleased if he saw any nuts. haha good times :)
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asicsp超过 1 年前
Previous discussion: <a href="https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=23501021">https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=23501021</a> <i>(731 points | June 12, 2020 | 362 comments)</i>
JR1427超过 1 年前
I can&#x27;t be bothered to read the article, but I recently discovered I can lose weight fairly easily by, wait for it... just eating a little bit less of everything I already eat. Other than that, the only conscious change was to sometimes substitute a chocolate snack with an apple.
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daco超过 1 年前
&gt; Avoid sugar like the plague, [...]including to a lesser extent natural sugar (apples, bananas, pears, etc - we’ve “weaponized” these fruits in the last few hundred years via strong artificial selection into actual candy bars), berries are ~okay.<p>Is avoiding fruits a good recommendation?
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francasso超过 1 年前
Great post, I had a different experience with the diet though. I lost 17kg in circa 4 months (an average of 1% body mass per week) while eating mostly carbs (240 g of pasta a day, 3 or 4 fruits) and vegetables. A couple of times a week I would eat 300g of chicken. The only physical exercise I do is running for 20 to 30 mins 3 times a week.<p>I have to say I&#x27;m quite happy with the diet, I basically never feel hungry and I love pasta so it&#x27;s enjoyable. Obviously you can&#x27;t just cover the pasta in a calorie dense sauce and expect to lose weight, you still need to keep an eye on the calories.
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m463超过 1 年前
interesting but it doesn&#x27;t touch on blood sugar and insulin. Insulin is what tells your body to store the excess glucose circulating in your blood in your fat cells. manage your blood sugar for good things.
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hxelk1超过 1 年前
About a year ago, I did two extended water fasts (24 and 16 days, about 8 weeks apart). I wanted to do a single 40 day one (just for kicks, to see if I last) but stopped after 24 days as I wasn&#x27;t feeling well.<p>I&#x27;ve lost 18 kg during the first one (102 kg -&gt; 84 kg), then quickly regained about 4 kg, and lost about 10 kg during the second one (88 -&gt; 78). After the second fast, I started resistance training between two and four times a week (with a brain-endowed gym coach). I&#x27;m currently down 14 kg (88 kg), but gained quite a lot of muscle.<p>Though I can&#x27;t recommend water fasting on blanket terms, if you&#x27;re like me and you prefer short-term intense stress to long-term baseline stress, you may find that it&#x27;s a great way to lose a lot of weight quickly, start feeling better about yourself and what your body is capable of, and get on the path to a healthier life style.<p>It was truly a remarkable experience.<p>For me, the trigger was <a href="https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=yaWVflQolmM">https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=yaWVflQolmM</a>.
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phkx超过 1 年前
<a href="https:&#x2F;&#x2F;karpathy.github.io&#x2F;2020&#x2F;06&#x2F;11&#x2F;biohacking-lite&#x2F;" rel="nofollow noreferrer">https:&#x2F;&#x2F;karpathy.github.io&#x2F;2020&#x2F;06&#x2F;11&#x2F;biohacking-lite&#x2F;</a><p>please use https links
pallas_athena超过 1 年前
This has been the &#x2F;fit&#x2F; sticky basically forever, and it&#x27;s always a great read: <a href="https:&#x2F;&#x2F;liamrosen.com&#x2F;fitness.html" rel="nofollow noreferrer">https:&#x2F;&#x2F;liamrosen.com&#x2F;fitness.html</a>
kashif超过 1 年前
Wow, how much time is spent in composing these detailed and well illustrated posts!
liampulles超过 1 年前
My biggest problem is eating something that makes me feel full, tastes good, can be prepared easily (or at least cookable and storable in bulk) and that does not turn into fat.<p>Very open to suggestions here
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mfld超过 1 年前
Related question: is anyone happily using a walking pad or similar while coding?
jrflowers超过 1 年前
TLDR:<p>&gt; maintaining an average deficit of 500kcal per day did lead to about 60% of the expected weight loss over the course of a year.
WithinReason超过 1 年前
(2020)
lagt_t超过 1 年前
Eat everything, eat balanced, count calories. Everything else is bad advice.
peteforde超过 1 年前
I am confident that I&#x27;m in good company when I say that I hit this sort of paragraph like a brick wall:<p>&gt; Do not drink any calories (no soda, no alcohol, no juices, avoid milk). Avoid sugar like the plague, including carbohydrate-heavy foods that immediately break down to sugar (bread, rice, pasta, potatoes), including to a lesser extent natural sugar (apples, bananas, pears, etc - we’ve “weaponized” these fruits in the last few hundred years via strong artificial selection into actual candy bars), berries are ~okay. Avoid processed food.<p>Look, I have nothing but respect for people who can read that and think, oh, cool, I hate everything that tastes good, is easy to access and leaves me feeling satisfied.<p>For those of us who are still yoked in service to evil things like rice, this paragraph just makes us feel like we&#x27;re fucked.<p>Also: even introverts who love cooking at home occasionally have to go for dinner with clients, relatives or friends. While it&#x27;s true that you can just order some naked bitter greens, this often doesn&#x27;t feel like a socially normal thing to do (even though norms are changing, especially in large and progressive cities).
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thomasfromcdnjs超过 1 年前
Everyone should just try carnivore, it is legit.
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lifeline82超过 1 年前
Human lost 1degree celsius of bodytemp in the last century.<p>Base metabolic rate dropped 10% in the last 30 years.<p>Modern diet are triggering torpor mechanism in human, blocking them into turning sugar to heat (thermogenesis), forcing them to store it into fat.<p>An american aged 20 in 1970 would have 5 times more chance to be obese in 2000 compared to a french or swiss of same age, while consumming on average 500calories less per day which represents a deficit bigger than 7millions calories over 30 years.
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antirez超过 1 年前
Estimating calories spent with the Apple Watch is not the best way. Just calculate your TDEE as an average, and in a conservative way (if you go to the gym 3 times a week and sit for your daily work you are <i>moderately</i> moving at best). Then use a deficit of 350 (if you are already quite fit) or 500 calories day. Make sure you don&#x27;t cut too much on any specific macro especially protein while eating at a deficit, and finally lift weights <i>while</i> you are losing weight, to protect muscles over fat. To have the habit of doing 10k steps per day is great, I do it, but I noticed that most people struggle, so this may be something you add gradually. There is no need to complicate things too much.<p>Make sure to: 1. Use an app like MyFitnessPal to track your calories. 2. Never use cheat days, when you don&#x27;t eat clean (but must be a rare occasion) always stay inside your calories. Remember: a cheat day may compensate 5&#x2F;6 days of eating at 350cals deficit VERY easily.
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