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Aspirin 81 (2019)

99 点作者 hippich超过 1 年前

10 条评论

userbinator超过 1 年前
I knew it&#x27;d be related to a unit conversion after the first paragraph. When regulations require units to be metric, but the actual quantity remains unchanged, this is the result.<p>Similarly, in the electronics industry, there are connectors whose pitch (distance between pins) is specified as 2.54mm. Not 2.5, but 2.54, which turns out to be exactly 0.1 inches, or &quot;100 thou&quot; in machinist&#x27;s parlance. Just to add to the confusion, there are also &quot;pure metric&quot; parts originating in the East with exactly 2.5mm pitch, which seems to fit the imperial ones, but only when the pin count is low enough that the difference is within tolerance.<p>It&#x27;s worth noting that most if not all of these odd values seem to be metrications of customary units; I can&#x27;t seem to think of any examples of the opposite.
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legulere超过 1 年前
Another place you’ll see weird doses is salts. They have a higher molecular weight than the base chemical. For instance one size is 684 mg Ibuprofen-DL-Lysin. It’s equivalent to 400mg of Ibuprofen.
thenerdhead超过 1 年前
Interesting they didn&#x27;t mention the studies of why low-dose gained popularity as some of the initial study amounts were quite high! (up to 1g):<p><a href="https:&#x2F;&#x2F;www.ctsu.ox.ac.uk&#x2F;research&#x2F;british-doctors-study" rel="nofollow noreferrer">https:&#x2F;&#x2F;www.ctsu.ox.ac.uk&#x2F;research&#x2F;british-doctors-study</a><p><a href="https:&#x2F;&#x2F;biolincc.nhlbi.nih.gov&#x2F;studies&#x2F;cdp&#x2F;" rel="nofollow noreferrer">https:&#x2F;&#x2F;biolincc.nhlbi.nih.gov&#x2F;studies&#x2F;cdp&#x2F;</a><p><a href="https:&#x2F;&#x2F;biolincc.nhlbi.nih.gov&#x2F;studies&#x2F;amis&#x2F;" rel="nofollow noreferrer">https:&#x2F;&#x2F;biolincc.nhlbi.nih.gov&#x2F;studies&#x2F;amis&#x2F;</a><p><a href="https:&#x2F;&#x2F;www.nejm.org&#x2F;doi&#x2F;full&#x2F;10.1056&#x2F;nejm198907203210301" rel="nofollow noreferrer">https:&#x2F;&#x2F;www.nejm.org&#x2F;doi&#x2F;full&#x2F;10.1056&#x2F;nejm198907203210301</a>
Plankaluel超过 1 年前
This seems to be a US (UK?) thing? At least here in the German speaking countries in Europe aspirin also has nice round numbers. A dosage for heart attack prevention is usually 100mg. Normal dose is 500mg
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bobsmooth超过 1 年前
I like this website. All the articles are written by med students. Each one has its own air of &quot;I&#x27;m writing this article to impress my professor.&quot; It&#x27;s cute.
PopAlongKid超过 1 年前
This is also sometimes called &quot;baby aspirin&quot;.[0]<p>I remember a conversation with a doctor where I casually mentioned that baby aspirin must have been created for babies, he was slightly aghast and and said no, you do not want to give it to babies!<p>[0]<a href="https:&#x2F;&#x2F;www.nhs.uk&#x2F;medicines&#x2F;low-dose-aspirin&#x2F;who-can-and-cannot-take-low-dose-aspirin&#x2F;" rel="nofollow noreferrer">https:&#x2F;&#x2F;www.nhs.uk&#x2F;medicines&#x2F;low-dose-aspirin&#x2F;who-can-and-ca...</a>
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lostlogin超过 1 年前
&gt; In the apothecary system, the base weight was derived from the weight of a grain of barleycorn.<p>My god. So not only is shoe sizing done in barleycorns, so is medicine.<p><a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Shoe_size" rel="nofollow noreferrer">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Shoe_size</a>
Mistletoe超过 1 年前
I just always assumed it was ~1&#x2F;4 of the normal 325 mg dose.
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MichaelRo超过 1 年前
I&#x27;ve never, ever used aspirin in my entire life as far as I recall.<p>It&#x27;s an NSAID, right? Which means it&#x27;s bad for the stomach lining. So when I do have a high fever or a crushing headache, I&#x27;ll use ibuprofen, which seems to me &quot;stronger&quot; than aspirin (I&#x27;m not a doctor, it&#x27;s just how I perceive it). For short time, several days, and by the end I do feel my stomach saying &quot;no more of this&quot;.<p>And when there&#x27;s no need for &quot;strong&quot; NSAID, well then I won&#x27;t use any at all. Maybe use paracetamol.<p>Either way I never got an use for aspirin.
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xorcist超过 1 年前
If anyone else wonders, Aspirin is a trade name for regular ASA (acetylsalicylic acid) painkillers.
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