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Microbiome diversity protects against pathogens by nutrient blocking

1 点作者 skmurphy超过 1 年前

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skmurphy超过 1 年前
CONCLUSION &quot;Conclusion: Our results support the idea that more-diverse microbiomes can provide health benefits, specifically that they can improve protection against pathogen colonization. We also find that colonization resistance is a collective property of microbiome communities; in other words, a single strain is protective only when in combination with others. Crucially, although increased microbiome diversity increases the probability of protection against pathogens, the overlap in nutrient-utilization profiles between the community and the pathogen is key. Our work suggests a route to optimize the composition of microbiomes for protection against pathogens.&quot;<p>Related article: <a href="https:&#x2F;&#x2F;www.medscape.com&#x2F;viewarticle&#x2F;we-know-healthy-gut-fights-infection-new-study-reveals-how-2023a1000w2k" rel="nofollow noreferrer">https:&#x2F;&#x2F;www.medscape.com&#x2F;viewarticle&#x2F;we-know-healthy-gut-fig...</a>