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Noisy brain may underlie some of autism's sensory features

242 点作者 wjb3超过 1 年前

19 条评论

lcnPylGDnU4H9OF超过 1 年前
I&#x27;m one who has identified much with descriptions of Autism but never been diagnosed. In particular, the descriptions of monotropism[0] feel like a personal attack. :) The article doesn&#x27;t seem to mention it but it&#x27;s common to see similar commentary from diagnosed autistic people who have been introduced to the idea.<p>Now just to find a competent neurologist who&#x27;s willing to run a brain scan.<p>0: <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Monotropism" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Monotropism</a>
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tbalsam超过 1 年前
Hi! I&#x27;m rather autistic.<p>This is a straightforward consequence of the bias-variance tradeoff, autistic brains tend to get too much information which is mathematically indistinguishable from noise.<p>This is why many of the repetitive patterns, social blindness, strong habituation, meltdowns, shutdowns, isolation, etc, work, they are informationally-linked coping mechanisms.<p>It is weird to me how advanced in some areas we are and how pop sci or culturally narrative driven in others. These are some extraordinarily basic ideas from basic and moderate information theory, there are more but it is difficult for me to summarize well and distinctly.<p>Everyone go read Shannon, then Varley&#x27;s info theory for complex system scientists. So many brain (and otherwise) phenomenons make sense and have strong predictive power for the complexity of the model, but that is sort of trivial since the brain does operate with informational dynamics by default.
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idbehold超过 1 年前
I don&#x27;t think this is the same thing as &quot;noisy brain&quot;, but I&#x27;m wondering if anyone else has experienced this before since it sounded similar. Sometimes, typically when I&#x27;m sick and I&#x27;m trying to sleep through the symptoms (e.g. sleep all night and all day), it seems like my brain gets bored or something and suddenly I cannot stop thinking&#x2F;dreaming about <i>something</i>. That something is different every time it happens, but it&#x27;s the same thing over and over repeating in my head. Eventually my head starts to hurt and I&#x27;m seemingly forced to be awake as it is the only way to stop this.
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growingkittens超过 1 年前
A lot of autism and disability research sounds like it&#x27;s written from the &quot;outside in&quot; - like peering into a window vs. being in a house.<p>I wonder how much research engages disabled people about their experience vs. observation or rote, systematic questions with assumptions.
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acheong08超过 1 年前
Somewhat related:<p>I pretty much have to blast random noise to stop my brain from going weird places when I’m trying to sleep.<p>Some weird examples: - Simulated conversations between random people. I might not even be involved - Wait did I remember to do this? (Usually something related to code) - Geometric nightmares (it’s hard to describe. I’m awake and conscious but there’s a large expanding object in my head and it makes me want to jump out the window)<p>Had issues for years until I realized that putting on podcasts in foreign languages or just random assortments of sounds (no patterns or else I’ll think about it) stops it from wandering.<p>Is this a case of a noisy brain or do I have actual issues?
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rpmisms超过 1 年前
I have a feeling this might be the cause of the Ballmer peak. I&#x27;m ASD, used to be way worse, grew partially out of it, but when it&#x27;s bad, the Ballmer peak makes me function like a normal human with the focus of an autist. The rest of the time, it&#x27;s a normal buzz.
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Solvency超过 1 年前
What about non-autistic migraine sufferers with extreme tendency towards sensory overload?<p>eg: smells especially fragrances, loud noises, ultra quiet noises, repetitive noises, too many people talking at once, etc?<p>Half of those can trigger a migraine. The other half just overwhelm me to where I feel incredible stress and need to remove myself.<p>But zero other autistic symptoms.
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gtsnexp超过 1 年前
It makes one wonder about the hyperconnectivity hypothesis: <a href="https:&#x2F;&#x2F;academic.oup.com&#x2F;cercor&#x2F;article&#x2F;18&#x2F;4&#x2F;763&#x2F;281733" rel="nofollow">https:&#x2F;&#x2F;academic.oup.com&#x2F;cercor&#x2F;article&#x2F;18&#x2F;4&#x2F;763&#x2F;281733</a>
Anotheroneagain超过 1 年前
This has no chance of leading anywhere. You&#x27;d need to figure out what&#x27;s wrong with other people.<p>Move more than 50 years back, and the autist would be the normal one.<p>Move anywhere from the highly westernized world, and the autist will be the normal one.<p>The other people are brain damaged.
aantix超过 1 年前
Does anyone else find that brain noisiness and ruminations reduce as you ingest more magnesium?
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keepamovin超过 1 年前
Can someone explain what this means?<p><i>“It’s nice that they use hindpaw stimulation as it adds a translational component” says Anubhuti Goel, assistant professor of psychology at the University of California, Riverside, who was not involved in the study. Past research has often opted for whisker stimulation, which is clearly not relevant to people, she says.</i><p><i>Translational</i> means it can translate more easily to people? I don&#x27;t really get it tho.
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Lemontology超过 1 年前
A multi-&quot;salt&quot; magnesium plus some glutathione antioxidant could temporarily calm some of the noise. Look into trans-cranial ultrasound (low power for 30-90 second sessions once or twice a day separated by at least 4 hours) (but this isn&#x27;t even beyond trials yet), and Earthing which is stepping out barefoot onto the ground). Then vitamin C to recycle the glutathione, protecting it from its breakdown through its job.<p>All of these therapies would be calming inflammation and oxidative stress (both related to each other and to stray&#x2F;excess electrical charges in the wrong places or out of control).<p>The magnesium I would use is &quot;Magnesium Breakthrough&quot; by &quot;BIOptimizers&quot; since it contains a large variety of salts. The bio-availability and especially the preferential uptake into specific organs...of Mg seems to be dependent on form, or salt.<p>And MIT students, a few years back, invented Magnesium-Threonate is also of therapeutic use as one possible tool, since it increases synapse density and neuroplasticity. Giving the chance of a brain to basically re-wire itself can be helpful when it is not functioning properly.<p>Lastly, fish oil, not snake oil, is going to help the body make the best membrane-encapsulated neuron bodies so that the brain is shuttling its neurotransmitters (which are basically signaling molecules) in a smooth and balanced functional pattern.<p>Other areas for YOU to RESEARCH before purchasing anything are these two things: Probiotics (like Seed DS-01), and Light. Look for a red and infrared light for winter and even summer use. It modifies the power of mitochondria. See this study: <a href="https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3179978&#x2F;#:~:text=While%20a%20large%20population%2Dbased,children%20with%20ASD%20(12)" rel="nofollow">https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3179978&#x2F;#:~:tex...</a>.<p>It always helps to be the doctor but if you can&#x27;t be for lack of time or dont have a naturally discerning mind, then get an opinion from a hormone or sports clinic which is designed to optimize, not a family doctor who wants food on kids&#x27; plates rather than competition with supplements. And your kid does need to eat food too, as a base. It might just be that doctors have an inborn instinct to protect their valuable secret knowledge from falling into three wrong hands like a Google algorithm unless you have the right keywords, then you&#x27;ll be rewarded with the right knowledge. I&#x27;d like a conversation of such insights as you might have about this and autism, given the fact that also when I was a child, I felt like I was pretty much just watching the life around me and taking notes, or not developing attention and communicating with kids my age in school or making friends.<p>If you want your kid to talk more but they have autism, maybe introduce from an interest of their&#x27;s to a conversational style designed to be technical and teach the vocabulary of the thing that they like learning about.
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CitizenKane超过 1 年前
I&#x27;m autistic and while it&#x27;s nice to see ongoing research, I can&#x27;t help but feel like this misses the point somewhat.<p>In particular I&#x27;ve seen a number of studies that make the jump from Fragile X syndrome to autism which I think is ill advised to say the least. There are a large number of genes[1] that are related to autistic individuals, and it&#x27;s a very heterogeneous condition. In particular many, perhaps even most autistic individuals don&#x27;t suffer from intellectual disability, don&#x27;t have any physical characteristics which would set them apart from others, and don&#x27;t tend to have problems with memory. All of these are characteristics of Fragile X syndrome.<p>&gt; “Imagine being at a party, talking to a friend while music is playing in the background,” Frick says. “You have to integrate the sound of their voice with the movement of their lips.” But if there’s variability in sensory processing, socializing will be more challenging, he says.<p>And I&#x27;ll take issue with this in particular. Frankly, the social issues of autistic individuals are wildly overstated and can be easily explained. Believe me, I know quite a few autistic folks and none of them have issues understanding when someone is speaking, we can tell. However, trying to sync up different minds that operate in different ways is a difficult problem.<p>Even among men and women with the same neurotype there&#x27;s enough difference to cause _substantial_ misunderstandings. Enough ink has been spilled on the topic of relations between the sexes to fill oceans. And the difference between neurotypes is far more substantial than the difference between sexes in this regard. It&#x27;s very easy for me to socialize with other autistic folks, I&#x27;ve had many conversations that have lasted hours on end. Doing the same thing with someone who is neurotypical though is much more difficult, and usually requires a willingness to put up with the awkwardness of not having the same vibe.<p>Finally, I won&#x27;t go into anything about using mouse models for complex neurological conditions at the moment. But suffice to say, this article would be more properly titled &quot;Noisy brain may underlie some of Fragile X syndrome&#x27;s sensory features&quot;, but that probably doesn&#x27;t get the same amount of attention.<p>[1] <a href="https:&#x2F;&#x2F;gene.sfari.org&#x2F;" rel="nofollow">https:&#x2F;&#x2F;gene.sfari.org&#x2F;</a>
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swayvil超过 1 年前
My bet is on &quot;uncommon attention management strategy&quot;.
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sublinear超过 1 年前
Autism is the biggest racket going for the majority of diagnoses. You&#x27;re not &quot;not neurotypical&quot; you&#x27;re just neglected and being sold.
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wegfawefgawefg超过 1 年前
The connection between noise and the emergent consequent of that noise being autism is quite an assumption. Even with the gene in common
ssl-3超过 1 年前
As an undiagnosed but frequently-accused autistic person:<p>&gt; Up to 90 percent of autistic people report sensory problems, including heightened sensitivity to sounds or an aversion to certain smells. Yet others barely register sensory cues and may seek out sensations by making loud noises or rocking back and forth.<p>I couldn&#x27;t read anything after that last sentence.<p>It seems like nonsense to me, and therefore it seems that everything after it is also likely to be nonsense.<p>I don&#x27;t (and haven&#x27;t) done things like make loud noise or rock back and forth because I somehow seek to have more sensation. But I have done things like that because the sensations I am perceiving are too intense (even if those sensations do not exist outside of my own head).<p>In normal daily discourse, the last thing I want is <i>more</i> uncontrolled and inescapable stimulation.<p>And when uncontrollable stimulation gets to be too much (which can happen in a quiet and empty room, or a very loud and busy room full of colors and scents) and becomes overwhelming, I sometimes seek to whelm myself with things that can be controlled.<p>But that&#x27;s never because I&#x27;m seeking more. It can be because I want or sometimes <i>need</i> for the noise (eg, the scents, scenes, tastes, sounds, physical sensations, and internal noise like pain and internal dialogue[s] and strong emotions) to cease, but since that is often impossible then the best I can do is give myself something else that I can control to focus on.<p>And that could mean making loud noises, or rocking. It can also include literally running away, or vocal outrage that surprises anyone around. The antidote could include lots of things.<p>But it&#x27;s always just an attempt at an antidote; it isn&#x27;t ever an attempt to feel <i>more</i>.<p>I think that if &quot;up to 90 percent of autistic people report sensory problems&quot; is true, then &quot;at least 10% of autistic people are completely misunderstood&quot; must also be true.
bitxbitxbitcoin超过 1 年前
Noisey as in - virtual snow kind of noisey?
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jordiburgos超过 1 年前
Or may not.