From the submitted article:<p>"Neal Freedman, Ph.D., Division of Cancer Epidemiology and Genetics, NCI, and his colleagues examined the association between coffee drinking and risk of death in 400,000 U.S. men and women ages 50 to 71 who participated in the NIH-AARP Diet and Health Study. Information about coffee intake was collected once by questionnaire at study entry in 1995-1996. The participants were followed until the date they died or Dec. 31, 2008, whichever came first."<p>Collecting data about coffee use only once would of course miss collecting data about people whose habits changed during the course of the study.<p>"The researchers found that the association between coffee and reduction in risk of death increased with the amount of coffee consumed. Relative to men and women who did not drink coffee, those who consumed three or more cups of coffee per day had approximately a 10 percent lower risk of death."<p>Looking at the data to see if there is a dose response is a key issue in observational studies of this kind that many other studies miss. This isn't the last word on the subject, for the reason mentioned above and for other reasons mentioned in other comments, but at least here the study authors are treating coffee use as a quantitative independent variable and not just as a binary variable.<p>For the record, I began daily use of coffee (one cup each morning with breakfast) only after age forty. I asked around a long time before learning how to establish a habit that would not spiral into increasingly heavy use and physiological tolerance that would keep me upping my dosage for years and years and years. I come from a family with varying coffee-drinking habits but generally long lifespans.