A mentor of mine now has very poor eyesight due primarily to age. It's affected his ability to use a computer significantly and even his ability to concentrate on a task for sustained periods of time. Also, a friend of my wife's has macular degeneration, and at time of writing has 30% or less of his eyesight remaining.<p>I find my own eyesight is starting to deteriorate (though with prescription lenses it's still pretty good), so in light of this and the above I'm definitely interested in how blind programmers work; accordingly, I've started experimenting with Emacspeak so that, if I ever go totally or effectively blind, there's still a pathway that I can use so that I can continue to computer effectively (including programming) without sight.