Life-changing cream to treat skin cancer moves closer to reality

It has too few details. It looks like very preliminate research. Clicking here and there, I got this patent <a href="https:&#x2F;&#x2F;patentscope.wipo.int&#x2F;search&#x2F;en&#x2F;detail.jsf?docId=WO2021248189" rel="nofollow">https:&#x2F;&#x2F;patentscope.wipo.int&#x2F;search&#x2F;en&#x2F;detail.jsf?docId=WO20...</a> that appears to be a molecule that disrput <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Proline#Cis%E2%80%93trans_isomerization" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Proline#Cis%E2%80%93trans_isom...</a>

Having had a look at it, it seems like this involves a molecule (Q2361) closely related to tacrolimus that is capable of binding to FKBP12 where tacrolimus would normally bind but without affecting the function of FKBP12.[1]<p>This seems to be useful in the specific case of people on long term tacrolimus as it locally antagonises tacrolimus activity in the skin to reduce cancer risk.<p>[1] <a href="https:&#x2F;&#x2F;jitc.bmj.com&#x2F;content&#x2F;jitc&#x2F;11&#x2F;9&#x2F;e006783.full.pdf" rel="nofollow">https:&#x2F;&#x2F;jitc.bmj.com&#x2F;content&#x2F;jitc&#x2F;11&#x2F;9&#x2F;e006783.full.pdf</a>

&gt;in organ transplant patients<p>It doesn&#x27;t say if this has any effect for non-immunosuppresive-related skin cancer.