It's interesting because I just started taking Qelbree\Viloxazine (a selective norepinephrine reuptake inhibitor), and even though I feel great I have a ton of trouble staying asleep. It seems to be a common complaint among folks talking it.<p>Before this, I took Strattera\Atomoxetine (which has the same method of action) for at least five years. And while falling asleep has long been difficult for me, staying asleep hasn't been.<p>Not quite sure how my experience relates, but makes me wonder if either too much norepinephrine also adversely impacts sleep or if I'm sleeping more "efficiently," so to speak, which is why I wake up feeling rested.<p>I don't remember any sort of similar experience when taking Effexor about a year ago, but I don't believe I ever reached a high enough dosage for the norepinephrine reuptake to take effect.