Woman who had pioneering cancer treatment 18 years ago still in remission

If you like stuff like this (i.e., beating cancer), badger your reps to get the NIH back up and running!<p>This particular work came out of at least 3 NIH grants and indirectly relies on a whole lot more.

Recruiting immune cells for cancer intervention is the future, but it will still take a while to get there.<p>&gt;&gt; Over seven years that followed the therapy, 12 patients died due to relapsed neuroblastoma. Among the seven that survived beyond this point, five were cancer-free when given the CAR T-cell therapy but had previously been treated for neuroblastoma using other approaches and were at high risk of relapse. All five were disease-free at their last follow-up, between 10 and 15 years after the CAR T-cell therapy, although the team note they may already have been cured when the therapy was administered.

A doctor in Australia has been cancer free for almost 2 years after treating his brain cancer with Car-T therapy<p><a href="https:&#x2F;&#x2F;www.bbc.com&#x2F;news&#x2F;world-australia-69006713" rel="nofollow">https:&#x2F;&#x2F;www.bbc.com&#x2F;news&#x2F;world-australia-69006713</a>

&gt; &quot;All five were disease-free at their last follow-up, between 10 and 15 years after the CAR T-cell therapy, although the team note they may already have been cured when the therapy was administered.&quot;<p>&gt; &quot;The other two surviving patients had cancer that was actively growing or spreading when they received CAR T-cell therapy, but subsequently went into complete remission. One of these patients stopped participating in follow-up sessions eight years after treatment, but the other continued and has remained cancer-free more than 18 years.&quot;<p>Based on these statements, the evidence for this treatment is anecdotal at best. Only 2&#x2F;27 patients lived longer than 7 years.<p>(There are probably more advancements in the last 10-15 years that have increased efficacy)

Problem with CAR-T is still too expensive to use...<p>people should be investing a lot more in early stage drug discovery biotechs! A lot more!!! (I&#x27;m doing an early stage drug discovery biotech)

Can someone explain &quot;remission&quot; to me?<p>Perhaps I am missing something because to me, going 18 years without cancer after having cancer and going through treatment is...expected? Does canceer treatment not actually get rid of the cancer or something like that?

I have zero medical experience so take this question as it is in good faith. Assuming the process to do this was known, how difficult would it be for a reasonably intelligent person to implement this procedure on their own

I’ve been exposing myself to similar, vaccine induced T cell production to fight cancer, research recently due to a family member recently going through it with pancreatic cancer.<p><a href="https:&#x2F;&#x2F;www.mskcc.org&#x2F;news&#x2F;can-mrna-vaccines-fight-pancreatic-cancer-msk-clinical-researchers-are-trying-find-out" rel="nofollow">https:&#x2F;&#x2F;www.mskcc.org&#x2F;news&#x2F;can-mrna-vaccines-fight-pancreati...</a><p>My family member was ineligible for the trial due to requiring chemo before surgery due to ca19-9 markers being above the limit for surgery eligibility.<p>Here are some of my observations as someone forced to the outside:<p>I read the 2017 and phase i papers.<p>They are both very mathy and talk more about the life spans of their induced T cells than their patients.<p>Looks like phase i was 19 patients (16 given the vaccine), 2 recurred, one died, they seem to want to blame the patients’ immune system.<p>The study is: surgery, vaccine, then 12 cycles of chemo regiment, then vaccine booster.<p>I was frustrated to see a lack of any search results for “diet”, “nutrition”, “sugar”, “glutamine”, in either paper.<p>I think the mathy science is cool, and a necessary component, but focusing on pharmaceutical solutions and calculating their efficacy based on if their intended biological reaction occurred, seemingly oblivious of, or defiantly ignoring, lifestyle change appears misguided.<p>Diet and exercise is insufficient on its own, but due to the vast differences in individual diets, studies like these should include lifestyle requirements as a control.<p>Especially if they are going to point at a patients immune system.<p>Diet effects on both immune system function and specifically targeting cancers is uncontroversial and scientifically supported.<p>Why are these two research efforts so siloed from each other?!

Must be way way more complicated than just find the cancer protein, make a special cell and inject

Bro didn&#x27;t you know you can inject Ivermectin directly into your balls and it cures your cancer? Duh.

People go into cancer remission without any treatment. Single point isn&#x27;t data, not proof of anything.