I am not saying the author's remarks are not interesting, but they live in a vacuum. For most projects, the resources spent on the "serving" part of your web service are a small portion of the actual expenses. In many cases, it's going to be less than 1%. Going from 0.1% to 0.01% is not a significant improvement.
A typical Django-based application has a lot of non Python code that is running separately and the performance of Django or Python itself are mostly irrelevant.
If your application is a TODO app and you have billions of users, maybe yeah.