I highly, highly recommend uv. It solves & installs dependencies incredibly fast, and the CLI is very intuitive once you've memorized a couple commands. It handles monorepos well with the "workspaces" concept, it can replace pipx with "uv tool install," handle building & publishing, and the docker image is great, you just add a FROM line to the top and copy the bin from /uv.<p>I've used 'em all, pip + virtualenv, conda (and all its variants), Poetry, PDM (my personal favorite before switching to uv). Uv handles everything I need in a way that makes it so I don't have to reach for other tools, or really even think about what uv is doing. It just works, and it works great.<p>I even use it for small scripts. You can run "uv init --script <script_name.py>" and then "uv add package1 package2 package3 --script <script_name.py>". This adds an oddly formatted comment to the top of the script and instructs uv which packages to install when you run it. The first time you run "uv run <script_name.py>," uv installs everything you need and executes the script. Subsequent executions use the cached dependencies so it starts immediately.<p>If you're going to ask me to pitch you on why it's better than your current preference, I'm not going to do that. Uv is very easy to install & test, I really recommend giving it a try on your next script or pet project!