Everything you've tried seem like "normal things". Maybe you need to do something <i>really</i> different.<p>If you can, travel. But not as you might normally travel, get right out of your comfort zone. Travel to very different cultures, places where you don't speak the language, travel very cheaply. Cheap travel is slow travel and that gives you time to be alone with yourself, which might help. Don't plan anything, if you can. This travel doesn't have to be international. If you live in a large country there are places you can go, cultures you haven't seen, things you haven't seen, modes of transport you haven't tried.<p>Start something substantial. Learn to fly, power or glider. If you are near the ocean try scuba-diving. Join a car racing club. Anything. A club environment can help because, to some extent, others depend on you, and that can help you too.<p>You are down, but you should realize that no matter how low you think you are, there are others worse off than you. One possibility is to try to help some of those others. You do have some experience of what it feels like.<p>Whatever you think you might try, don't say "I don't want to start, I'm not interested enough". Just get started, burn your boats, get committed. After getting started resist the thought of bailing. See how it goes.<p>Ultimately it all depends on you. A life has many twists and turns. Good luck.