Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials<p>>In economic terms, estimates of the final cost of synthesis of DMNB-T6P are set to be in the region $300 per ton, which equates to a few cents per hectare at current rates of application. If this stimulated yield by the average of 10.4% that we observed from field trials (wet and dry years at 10 DAA application), then the increase in global wheat yield average of 3.6 tons per hectare would be 0.37 tons per hectare (worth an extra $116 per hectare (wheat price in February 2023)); this amounts to $25.6 billion globally (221 million hectares grown in 2021). With further improvements in formulation and adjuvants, it may be possible to reduce application dose rate and/or exceed the yield improvements presented here.