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Mass spectrometry method identifies pathogens within minutes instead of days

124 点作者 pseudolus2 天前

6 条评论

pbmonster大约 14 小时前
Would be interesting how much resolution they need for the diagnosis to be reliable.<p>Because high resolution mass spectrometers cost millions of dollars, and &quot;minutes&quot; for a diagnosis can mean that one spectrometer can only run 3 samples per hour - or 72 per day.<p>And while a research university can afford a million dollar spectrometer (and the grad students that run it), even a small hospital will create 72 bacterial swaps per hour - while absolutely not having the money to get 10 spectrometers with the corresponding technicians.<p>And the incumbent&#x2F;competitor - standard bacterial cultures - is cheap!
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rurban大约 14 小时前
Mass spectromity is a bit expensive. My company can detect a common plant virus reliable with multi-spectral imaging only. Normal hires B&#x2F;W cameras. 10 days before visible symptoms. SpexAI.com<p>Only vision scales. We did mass spectromity in Formula 1 because we had the money and it doesn&#x27;t need to scale.
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JR1427大约 13 小时前
You can identify quite a few pathogens with Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy. I think the machines for that are smaller and cheaper than mass spec machines.<p>see <a href="https:&#x2F;&#x2F;pmc.ncbi.nlm.nih.gov&#x2F;articles&#x2F;PMC5631018&#x2F;" rel="nofollow">https:&#x2F;&#x2F;pmc.ncbi.nlm.nih.gov&#x2F;articles&#x2F;PMC5631018&#x2F;</a> , and this company that is commercialising it <a href="https:&#x2F;&#x2F;microbira.com&#x2F;" rel="nofollow">https:&#x2F;&#x2F;microbira.com&#x2F;</a>
snalty大约 10 小时前
This is cool, but I still see sequencing and metagenomics as being the gold standard going forward.
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Inuit大约 4 小时前
I wonder how much resolution they need for diagnosis...
timetobuild大约 15 小时前
Super interesting! But mass spectrometry is an old method, why just now?
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