As I'm sure Patrick knows a first degree of accuracy you could of course substitute "Ireland" for "outside Silicon Valley" and the point about acquisitions is especially well made.<p>Even in London we're seeing that the companies here are giving investor valuations that simply 1/5 of the valley and on most levels I have to say that I can't blame the investors for their pessimism as there are so, so few exits here.<p>Exits (large or small) perform three important roles for establishing a startup scene:<p>1. They create wealth for founders who are themselves much more likely to become investors<p>2. They create wealth for investors. Whether an investor is actually in on a deal or not this changes their attitude and their optimism and makes them more likely to invest due to the perceived good climate<p>3. As Patrick said, they increase the likelihood of high calibre individuals doing startups. Good people can do very well in other jobs and if they see the likelihood of success in a startup as being negligible, they'll stay elsewhere.<p>All of these three tend towards self reinforcement which is powerful. It's worth noting that none of them depend on the net P&L from angel investment to be positive, only that the net gain in perception to be positive.<p>One of the simple reasons it's very hard to sell the types of companies we discuss on HN outside the valley is that to sell a company you really need to actually meet someone willing to buy a company. These things still tend to start face to face.<p>Outside the valley there are far fewer biz-dev teams and, perhaps more importantly, far fewer engineering teams. The types of companies that create a lot of wealth are usually product focussed and get bought by product / engineering teams. Most of those acquiring teams are based in the states. FB only has a very small outpost in London and while Google's is huge and does include engineering it's predominantly sales support and does not (as far as I know) make many purchases.<p>I was fortunate enough to be able to sell my last startup (Clickpass) but there is no way that would have happened outside the valley. For that reason among many others we're moving back out to SF in January. I love SF and I'm happy to move back but sad to leave London and my life here too. However I too have come to the conclusion that it simply doesn't make sense to be outside the valley, you just set the odds too far against yourself.