Cosma Shalizi's "null model of scientific inquiry" [1] seems relevant here. Basically it's a model where all published findings are due to the file drawer effect [2]. In such a model, scientific results will indeed have a "half-life" until they are overturned.<p>[1] <a href="http://masi.cscs.lsa.umich.edu/~crshalizi/weblog/698.html" rel="nofollow">http://masi.cscs.lsa.umich.edu/~crshalizi/weblog/698.html</a><p>[2] <a href="http://en.wikipedia.org/wiki/Publication_bias" rel="nofollow">http://en.wikipedia.org/wiki/Publication_bias</a>