Obviously I love bootstrap otherwise I wouldn't be building Jetstrap. But really, bootstrap is an extremely solid framework, and you can do a ton of customizations to make it look completely non-default (for example, our designer built our company site in a day with bootstrap+jetstrap which looks completely customized: <a href="http://drifty.co/" rel="nofollow">http://drifty.co/</a>).<p>You will implement the same structures if you don't use it, so you might as well take advantage of the framework and invest in a nice custom design.