TE
科技回声
首页24小时热榜最新最佳问答展示工作
GitHubTwitter
首页

科技回声

基于 Next.js 构建的科技新闻平台,提供全球科技新闻和讨论内容。

GitHubTwitter

首页

首页最新最佳问答展示工作

资源链接

HackerNews API原版 HackerNewsNext.js

© 2025 科技回声. 版权所有。

Poor-Quality Antidepressant Studies

1 点作者 techdog大约 12 年前

1 comment

lutusp大约 12 年前
It's too bad the author of this piece didn't include a reference to a remarkable study that combined published antidepressant studies, most of which found them to be effective, and studies that were funded, carried out, but then not published, which largely found them to be ineffective. The study's conclusion: "Meta-analyses of antidepressant medications have reported only modest benefits over placebo treatment, and when unpublished trial data are included, <i>the benefit falls below accepted criteria for clinical significance</i>." [Translation: antidepressants do not work.]<p>The study: <a href="http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0050045" rel="nofollow">http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fj...</a><p>After this study was published, it ought to have been replicated, or its conclusions called into question or falsified, or newer studies of greater scope be carried out, or antidepressant manufacturers be forced to include a warning on their antidepressant products: "This drug is actually a placebo".<p>But ... none of these things happened. The study had precisely no effect on the pharmaceutical industry or the public.