There was recently an interview posted here on HN about the end of antibiotics (<a href="http://www.pbs.org/wgbh/pages/frontline/health-science-technology/hunting-the-nightmare-bacteria/dr-arjun-srinivasan-weve-reached-the-end-of-antibiotics-period/" rel="nofollow">http://www.pbs.org/wgbh/pages/frontline/health-science-techn...</a>). In short, the interviewee Dr. Arjun Srinivasan was pleading for a serious conversation about what to do to further regulate their usage, because some bacteria are developing increased resistance to most, if not all, antibiotics available. What's stunning to me about all these articles is that, after all these alarms have been raised and as all the people responsible seem to be contemplating solutions to regulate antibiotic usage, nobody's mentioning alternative methods to fight bacteria. Following the afore mentioned article one commenter remarked that Dr. Srinivasan did a great job or spooking us, but there was absolutely no mention of bacteriophage during the interview, which got me curious. Turns out phage therapy (<a href="http://en.wikipedia.org/wiki/Phage_therapy" rel="nofollow">http://en.wikipedia.org/wiki/Phage_therapy</a>) has been used successfully for close to 100 years in Russia and Georgia. According to this Wikipedia page <a href="http://en.wikipedia.org/wiki/Bacteriophage" rel="nofollow">http://en.wikipedia.org/wiki/Bacteriophage</a><p><pre><code> Phages were discovered to be antibacterial agents and were used in Georgia and the United States during the 1920s and 1930s for treating bacterial infections. They had widespread use, including treatment of soldiers in the Red Army. However, they were abandoned for general use in the West for several reasons:
- Medical trials were carried out, but a basic lack of understanding of phages made these invalid.
- Phage therapy was seen as untrustworthy, because many of the trials were conducted on totally unrelated diseases such as allergies and viral infections.
- Antibiotics were discovered and marketed widely. They were easier to make, store and to prescribe.
- Former Soviet research continued, but publications were mainly in Russian or Georgian languages, and were unavailable internationally for many years.
- Clinical trials evaluating the antibacterial efficacy of bacteriophage preparations were conducted without proper controls and were methodologically incomplete preventing the formulation of important conclusions.
Their use has continued since the end of the Cold War in Georgia and elsewhere in Central and Eastern Europe.
</code></pre>
In other words the reason why western countries stopped considering them, and to some extent continue to shun them, is lack of understanding.<p>I am wondering then, if we have to have these "serious conversations" about regulation of antibiotics for the sake of the threat posed by over-consumption, how serious can it really be if we have to wear blinders and continue to pretend that what the Russians and Georgians have been doing is utter sorcery?