If you want boilerplate, the Yeoman collection tools: <a href="http://yeoman.io/" rel="nofollow">http://yeoman.io/</a> is what you need. There's boilerplate for a huge amount of projects, with generators of the parts (like: service for Angular, models for Ember, routes for Backbone...).
The angular-generator is a very complex piece of work, but is extremely efficient. I highly suggest you to try it twice: once to fuck things up, another to understand the good way.<p>You can eventually use these CSS and HTML skeletons (<a href="http://html5up.net/" rel="nofollow">http://html5up.net/</a>) to do something neat, but I don't think someone will judge you because you used bootstrap.<p>In term of javascript development, I've found SugarJs (<a href="http://sugarjs.com" rel="nofollow">http://sugarjs.com</a>) to be extremely productive and efficient for what I need, combined with the front-end framework of your choice.<p>And you, what's yours ?