I'm no scientographer, but it seems to me that a dependence on helium may be a stumbling point for getting cheap vacuum transistors to the market. The ongoing helium shortage[1] is driving the price of helium up which could make helium-based vacuum transistors expensive, limiting widespread adoption. It could be that high-speed helium vacuum transistors become a speciality product for those projects that feel the need justifies the additional cost.<p>[1] <a href="http://www.decodedscience.com/helium-shortage-situation-update-one-year-later/42314" rel="nofollow">http://www.decodedscience.com/helium-shortage-situation-upda...</a>