The biggest problem I've had with bootstrap is that it is so large. There is so much overhead. My company is working on a project and it would have taken a ton of work to port to bootstrap.<p>For lightweight grids that support dynamically sized containers, masonry was great. But there a ton of issues with keeping the content centered when the container changes size.<p>We dealt with this by using inline-blocked elements with tex-align: center, then appending invisible elements to maintain an apparent left-oriented grid: <a href="https://github.com/hangify/Central" rel="nofollow">https://github.com/hangify/Central</a>