When you take the legal complications away, the "marijuana business" is nothing but farming. Beyond that, it's farming involving a crop that is (relatively speaking) very cheap and easy to grow.<p>Once the laws are straightened out, I see no reason why big agribusiness won't completely crush all the startups entering this space. They have the scale, resources and experience to produce cannabis vastly cheaper than anybody else could hope to. A few small boutique farms might be able to eek out an existence (maybe we'll see "fair trade" marijuana?) but it's not anything I would ask a VC to put money into.