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How Much Caffeine Is Too Much?

124 点作者 2510c39011c5超过 10 年前

17 条评论

jonpaul超过 10 年前
I went to the ER (<a href="https:&#x2F;&#x2F;twitter.com&#x2F;jprichardson&#x2F;status&#x2F;522084579906052096" rel="nofollow">https:&#x2F;&#x2F;twitter.com&#x2F;jprichardson&#x2F;status&#x2F;522084579906052096</a>) about 2.5 weeks ago because I didn&#x27;t get enough sleep and drank way too much caffeine. My body just collapsed.<p>From October 5th through October 11th, I actively rejected sleep (2 - 4 hours of sleep) and took in quantities of caffeine ranging from 1.5 g to 2 g. (A cup of coffee has approx 100 mg and a strong energy drink has about 250 mg). I was preparing for launch of my product and subsequent YC application. On Saturday morning, October 11th, I had massive chest pains and I collapsed. Fortunately, everything is alright with my heart. Overall though, I felt incredibly stupid about my actions.<p>As hackers and entrepreneurs, it&#x27;s really easy to fall into the trap of your launch being the most important thing in the world. It&#x27;s not. You need to be healthy, as business is a marathon and you&#x27;ll be running for awhile.
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iamthepieman超过 10 年前
My first year in college I had a french press (a kind of coffee maker) and a tin of breath mints that had caffeine in them. One night, trying to finish a project, I drank an entire quart of strongly brewed coffee (~500mg)and ate the caffeinated breath mints like popcorn (30mg each)[0]. I recall walking down the dormitory hallways with extremely heightened senses. I was hearing whispers on the other side of closed doors and watching a fly buzz past me in what seemed like slow motion. I could feel the carpet texture through the soles of my shoes and time seemed to slow down.<p>At the time I thought it was one of the most incredible experiences of my life and vowed to repeat it sometime.<p>Thinking back I realize I was probably experiencing mild hallucinations and could have been on the verge of collapse.<p>edit: Added caffeine estimates.<p>[0]Can&#x27;t believe I found this. <a href="http:&#x2F;&#x2F;www.wegotcoffee.com&#x2F;mints&#x2F;zingo.php" rel="nofollow">http:&#x2F;&#x2F;www.wegotcoffee.com&#x2F;mints&#x2F;zingo.php</a>
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Jhsto超过 10 年前
Though the article does not take into an account the possibility that some may consume caffeine in powder form. You can find 100 grams, or over 7 times the lethal dose, for 13 bucks in Amazon [1].<p>As for who would use caffeine in such form are weightlifters and people interested in nootropics in general. I follow both communities online and from time to time I find some people overdosing caffeine by mistaking it to some other similar looking substance, like creatine or taurine. Though typical overdose has been about 3 grams, it has been enough to make the consumers force themselves to puke it out or get into ER.<p>I havent personally bought caffeine in pure form, but the idea has crossed my mind few times as these articles have started to pop out. I would not be surprised if caffeine would sooner or later be banned from being sold online.<p>[1] <a href="http:&#x2F;&#x2F;www.amazon.com&#x2F;BulkSupplements-Pure-Alanine-Powder-grams&#x2F;dp&#x2F;B00EIO4I5W&#x2F;ref=sr_1_5?s=hpc&amp;ie=UTF8&amp;qid=1414487723&amp;sr=1-5&amp;keywords=caffeine+powder" rel="nofollow">http:&#x2F;&#x2F;www.amazon.com&#x2F;BulkSupplements-Pure-Alanine-Powder-gr...</a><p>EDIT: tried to simplify few sentences
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hessenwolf超过 10 年前
Apparently, caffeine makes it harder to intake iron.<p><a href="http:&#x2F;&#x2F;fscn.cfans.umn.edu&#x2F;prod&#x2F;groups&#x2F;cfans&#x2F;@pub&#x2F;@cfans&#x2F;@fscn&#x2F;@admin&#x2F;documents&#x2F;asset&#x2F;cfans_asset_122645.pdf" rel="nofollow">http:&#x2F;&#x2F;fscn.cfans.umn.edu&#x2F;prod&#x2F;groups&#x2F;cfans&#x2F;@pub&#x2F;@cfans&#x2F;@fsc...</a><p>And anaemia, stemming from lack of iron, leads to fatigue and irritability, which both suck balls for coding.<p>edit: What did we learn in the article?<p>1. 140 cups will kill me.<p>2. Up to six cups a day will result in higher or lower mortality, depending on the study.<p>3. A study has shown that caffeine may lead to higher bad cholesterol.
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ludicast超过 10 年前
In February, I had an aortic dissection. That&#x27;s a big deal medical emergency with the kill ratio of a special forces operator.<p>Symptoms were similar to a heart attack, so it took a while to diagnose (John Ritter died of it, because they were treating him for a heart attack). In the ER they kept asking me if I was on coke, viagra, etc. Then someone brought up coffee.<p>I remember admitting that I had 6 cups that day, and thinking they&#x27;d stop taking me seriously. When they* finally figured out my medical situation and told me I needed to have IMMMEDIATE open heart surgery, the first thing I said was &quot;thank god I&#x27;m not a hypochondriac&quot;.<p>Then I worried about my family and work and shit like that. But thanks to coffee my first worry was they&#x27;d think I &quot;a bubblegummer&quot;.<p>* - &quot;they&quot; btw, was an awesome nurse and NOT the 3 doctors who saw me there.
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coldcode超过 10 年前
Your bodies reaction to coffee is interesting, the receptors for caffeine apparently expand up to a certain point, once you reach that level additional caffeine does not good for wakefulness but the side affects continue. It&#x27;s a ceiling you cannot go beyond but people often don&#x27;t recognize it.
mhartl超过 10 年前
It&#x27;s strange that the article hints at genetic differences in caffeine metabolism and sensitivity (&quot;Some people will get edgy from a weak cup of tea. For others, a double espresso is required to get them into the shower in the morning.&quot;) but doesn&#x27;t follow through on the implications. For example, my 23andMe results indicate that I&#x27;m a &quot;fast caffeine metabolizer&quot;, which is associated with a neutral to slightly lower risk of heart attack due to caffeine consumption, whereas slow caffeine metabolizers have a higher risk. In other words, it&#x27;s clear that the answer to the question &quot;How Much Caffeine Is Too Much?&quot; is &quot;It depends on your genes.&quot;
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benzimmer超过 10 年前
If you&#x27;re not a coffee person: <a href="http:&#x2F;&#x2F;www.caffeineinformer.com&#x2F;death-by-caffeine" rel="nofollow">http:&#x2F;&#x2F;www.caffeineinformer.com&#x2F;death-by-caffeine</a>
DanBC超过 10 年前
The article doesn&#x27;t talk about aggression. I&#x27;d be interested in seeing some good quality research comparing people&#x27;s responses to stuff when they&#x27;re had caffene vs not.<p>It&#x27;s frustrating that the evidence around mental health is so poor. I think that small amounts of caffeine destroy my sleep hygiene so I avoid it after midday. But it&#x27;d be great to know if a couple of cups of coffee in the morning was probably good or probably not good.
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waylandsmithers超过 10 年前
tl;dr: &quot;While clinicians may observe benefits and risks of caffeine intake, the effects are still being debated in academic circles.&quot;
karzeem超过 10 年前
This may be too Talebian a reaction, but isn&#x27;t the track record of &quot;take this-doesn&#x27;t-occur-in-significant-quanities-in-food chemical and your health will improve&quot; quite poor? Non-food chemicals are often very useful for acute interventions (e.g. antibiotics, chemotherapy), but at least in modern times, they almost always do more harm than good when taken long-term.<p>(To avoid getting sidetracked by chronic medicines that some people swear by, I&#x27;m directing this point more at non-food drugs that are designed to take people from normal health to great health rather than from a disease state back to normal.)
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ryno2019超过 10 年前
Exercise is an amazing alternative.<p>I&#x27;ll never cease to be amazed by how much more alert, focused and productive I feel when I take time away to get to the gym instead of grabbing another cup of coffee and keeping at it.
snarfy超过 10 年前
I remember a couple times I went to DefCon there was a guy with a booth selling pure caffeine powder in little baggies.<p>I didn&#x27;t start drinking coffee until my mid thirties. I can resoundingly say I slept better and woke up easier without it.
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utnick超过 10 年前
in the reddit nootropics forum the other day there was a post from someone who almost accidently OD&#x27;d on caffeine.<p>Alot of the users there use caffeine powder, and he had his bags of powder mixed up with his vitamin c powder and almost drank a drink with multiple grams of caffeine in it. He realized it at the last second and stopped.<p>moral of the story: caffeine has a fairly low lethal dose and can be dangerous when using the powdered form
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gimboland超过 10 年前
This guy knows: <a href="http:&#x2F;&#x2F;www.tmcm.com&#x2F;tmcm&#x2F;" rel="nofollow">http:&#x2F;&#x2F;www.tmcm.com&#x2F;tmcm&#x2F;</a>
ChaoticGood超过 10 年前
400 mg = too much<p>200 mg = too little
somberi超过 10 年前
Quoting from Pubmed (via nih.gov):<p>&quot;The present study compared the effects of caffeine on subjective arousal among introverts and extraverts.... caffeine improved the task performance of extraverts but overaroused introverts and thus impaired their performance.&quot;<p><a href="http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pubmed&#x2F;10472512" rel="nofollow">http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pubmed&#x2F;10472512</a>
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