> creativity is notoriously difficult to study in a laboratory setting<p>I'm really looking forward to the day when technology can more <i>directly</i> measure the effects of various substances on the body, rather than the inexact observation methods used today.<p>Take SSRIs, for example. Here's how it works. Patient tells doctor "I feel depressed". Doctor prescribes medicine. (A few weeks or months go by.) Doctor asks, "Well, how do you feel?"<p>We need to be able to say: "Over the course of your treatment, you ingested X milligrams of Zoloft, with an average concentration of Y in your bloodstream. Here's the 1-month graph. Your avg levels of serotonin were Z% higher than usual during this time. Your cortisol (stress hormone) level was C% lower. You slept an average of S hours per night, with E% improvement in deep sleep efficiency." etc.<p>At some point, the former is going to sound quaint and old-timey.