Alan Kay was inspired by the real world, mostly biology back when psychotropic substances were rather popular.
That's were the problems start.
The real world systems are:
1) unpredictable - except for those who can forecast the future.
2) Unreliable
3) Slow
4) Uncoordinated - except if you believe someone runs the world.
5) Unmaintainable - just ask someone on human maintenance (drug research etc).
6) Naturally autonomous<p>Point 6 is very critical, because in von-neumann architectures you will end up having a shared memory and trying to give an autonomous memory to each agent, will end up very suboptimal, and no zipper, COW of any other FP trick can change that.<p>You just cannot afford to write your software like the real world, and you don't even have intelligent agents of human ability as building blocks...