The term "hedge fund" covers a tremendous range of firms. That said I would look out for the same things you'd look out for in any funding arrangement: price, control, dilution, liquidation preference, unusual rights, etc. If you're just looking for money, it all spends the same as long as it doesn't come with onerous terms. However, you won't get any of the putative benefits of working with a "real" VC: access, guidance, services, follow-on funding, etc. You definitely do not want to end up with a cap table comprised of one line item for founders and one line item for the "hedge fund"'s investment on some weird-ass terms; that will make it nigh-on impossible to secure follow-on funding. I would feel best about taking this kind of money if I had a "real" VC as the lead investor and the hedge fund folks were minority, pari passu, and personally known to me. Also, DO NOT sign any document without legal support. Make the legal relationship, spend the money, understand what you're being asked to agree to, and PUSH BACK if you don't like the terms being offered. A broken structure is not the foundation you want.