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Ask HN: What are the greatest discoveries in the last few years?
33 条评论
zt将近 10 年前
CRISPR for gene editing:<p>"Since 2013, the CRISPR/Cas system has been used for gene editing (adding, disrupting or changing the sequence of specific genes) and gene regulation in species throughout the tree of life. By delivering the Cas9 protein and appropriate guide RNAs into a cell, the organism's genome can be cut at any desired location."<p>(From Wikipedia <a href="https://en.wikipedia.org/wiki/CRISPR" rel="nofollow">https://en.wikipedia.org/wiki/CRISPR</a>)<p>Edit: Hear a recent Radiolab episode on the topic (<a href="http://www.radiolab.org/story/antibodies-part-1-crispr/" rel="nofollow">http://www.radiolab.org/story/antibodies-part-1-crispr/</a>)
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bradneuberg将近 10 年前
The revolution in biotech happening from the discovery of the CRISPR process will be as important as the semiconductor in the long run: <a href="https://en.wikipedia.org/wiki/CRISPR" rel="nofollow">https://en.wikipedia.org/wiki/CRISPR</a><p>Neural networks via deep learning started showing incredible results the last few years (after about 40 years of development) across a range of fields, including speech recognition, machine vision, and more. It's still early days, but combining reinforcement learning with neural networks looks like it will be very exciting too: <a href="http://www.nature.com/nature/journal/v518/n7540/full/nature14236.html" rel="nofollow">http://www.nature.com/nature/journal/v518/n7540/full/nature1...</a>
BerislavLopac将近 10 年前
I would say, in no particular order:<p><pre><code> * the fact that many of the dinosaurs had feathers
* myriad of exoplanets
* water on Mars (and many other new data on the planet)
* Higg's boson (confirmed to 99.999% certainty)
* Neanderthal genes present in modern humans
* new ancient Mayan cities
</code></pre>
That's it from me for starters, hopefully others will join in.
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r2将近 10 年前
In solar cell research, the biggest recent breakthrough was probably the creation of efficient perovskite solar cells [1]. They're cheap, easy to make, and their efficiency in the lab is rising more rapidly than that of just about any other research cell since NREL began tracking (up from 3.5% in 2009 to 20.1% today) [2,3]. If their chemical stability problems can be resolved, they'll have big commercial applications.<p>[1] <a href="http://www.sciencemag.org/content/342/6165/1438.2" rel="nofollow">http://www.sciencemag.org/content/342/6165/1438.2</a><p>[2] <a href="http://www.nrel.gov/ncpv/images/efficiency_chart.jpg" rel="nofollow">http://www.nrel.gov/ncpv/images/efficiency_chart.jpg</a><p>[3] <a href="http://www.technologyreview.com/news/517811/a-material-that-could-make-solar-power-dirt-cheap/" rel="nofollow">http://www.technologyreview.com/news/517811/a-material-that-...</a>
jotux将近 10 年前
Not very "fundamental" but I'm very excited about low-power advancements in ICs. There are companies like AmbiqMicro making microcontrollers that are reaching 30uA/MHz and 100nA sleep modes. This is starting to make ambient and RF energy harvesting viable.<p><a href="http://ambiqmicro.com/low-power-microcontroller" rel="nofollow">http://ambiqmicro.com/low-power-microcontroller</a>
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natrius将近 10 年前
Blockchains. Distributed consensus is incredibly powerful. It will allow us to rebuild our society around individuals instead of corporations and governments that formed because economic transaction costs were so high that economies of scale (and sometimes the use of force) were required to coordinate our society.<p>All economic activity will be blockchain-mediated. It will make us wealthier and freer.
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jonmc12将近 10 年前
I thought the discovery of the quantity of distinct populations (~5k currently) and densities (relatively even) of upper-ocean viruses was perhaps an under-rated discovery that could lead to more advanced understanding of both the evolution of cellular organisms on earth and our current ecosystem. <a href="https://www.quantamagazine.org/20150521-ocean-viruses/" rel="nofollow">https://www.quantamagazine.org/20150521-ocean-viruses/</a>
chintan将近 10 年前
Mermistor (discovery in 1971 but actual implementation in 2008)<p><a href="http://arstechnica.com/information-technology/2014/06/hp-plans-to-launch-memristor-silicon-photonic-computer-within-the-decade/" rel="nofollow">http://arstechnica.com/information-technology/2014/06/hp-pla...</a>
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lalalandland将近 10 年前
Unraveling the link between brain, lymphatic system:
<a href="http://www.sciencedaily.com/releases/2015/06/150615094258.htm" rel="nofollow">http://www.sciencedaily.com/releases/2015/06/150615094258.ht...</a>
unusximmortalis将近 10 年前
Researchers at Audi are making synthetic diesel fuel using only water and air. Miracle? No. Science.<p><a href="http://money.cnn.com/2015/04/28/technology/audi-diesel-air-water/" rel="nofollow">http://money.cnn.com/2015/04/28/technology/audi-diesel-air-w...</a>
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riemannzeta将近 10 年前
CRISPR, blockchain, and direct connection between brain and lymphatics system are way bigger, but this was a big one for economics and political science:<p>Zero-Determinant Strategies in Iterated Prisoners' Dilemma
<a href="http://www.pnas.org/content/109/26/10409.full.pdf" rel="nofollow">http://www.pnas.org/content/109/26/10409.full.pdf</a>
PaulRobinson将近 10 年前
I'd say that in terms of what we are able to do next, Graphene wins by a long way. Graphene is remarkable stuff, literally.<p>I'd say in terms of impact on philosophy, religion and way of life, the large number of planets we're discovering.
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lalalandland将近 10 年前
An invention but also a dicovery:
The EmDrive (or RF resonant cavity thruster)
<a href="https://en.wikipedia.org/wiki/EmDrive" rel="nofollow">https://en.wikipedia.org/wiki/EmDrive</a>
etrautmann将近 10 年前
Grid cells are pretty cool, and thought to form the basis for spacial navigation in the brain, and the discovery of these cells in 2006 won this year's Nobel prize<p><a href="https://en.wikipedia.org/wiki/Grid_cell" rel="nofollow">https://en.wikipedia.org/wiki/Grid_cell</a>
robg将近 10 年前
How sleep washes the brain of toxins:
<a href="http://www.nih.gov/researchmatters/october2013/10282013clear.htm" rel="nofollow">http://www.nih.gov/researchmatters/october2013/10282013clear...</a><p>This mechanism could also be the cause of the refreshment we feel after a short nap or meditation. Much harder to study though!
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VLM将近 10 年前
A VERY specific request, no inventions, just things found and cataloged aka discovered.<p><a href="http://www.openexoplanetcatalogue.com/systems/" rel="nofollow">http://www.openexoplanetcatalogue.com/systems/</a><p>Also see pretty much every space probe of the "last few years". Pity you couldn't wait another month for the Pluto flyby, unless it completely fails there will be plenty to talk about.<p>I would imagine the biological sciences could list all kinds of interesting, possibly useful, critters.<p>The geologists and archeologists are always digging something cool up.
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gremlinsinc将近 10 年前
This sounds more like an AskReddit post than AskHN... but I'd say printable organs, smaller and smaller computer chips, commercialization of space flight, possible warp drive tech(may get us there in 100+ years, lol not expecting anything soon).. anti-aging (expected to double or triple life expectancy by 2050.) etc...
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JonnieCache将近 10 年前
While it's not really "great", the <i>absence</i> of new fundamental physics this century is certainly striking...<p>OTOH Quantum error correcting codes are pretty bananas. Won't be useful for a good while.<p><a href="https://en.wikipedia.org/wiki/Quantum_error_correction" rel="nofollow">https://en.wikipedia.org/wiki/Quantum_error_correction</a><p>EDIT: the correct answer is that gene editing stuff though.
eli_gottlieb将近 10 年前
The most wildly fundamental paper I have seen recently is last December's "Anytime Algorithms for Non-Ending Computations" by Calude and Desfontaines.<p>NOW HANDS OFF IT'S MINE! MINE I SAY!
figure8将近 10 年前
In nutrition and medicine, why red meat causes cancer in humans:<p><a href="http://blogs.discovermagazine.com/d-brief/2015/01/02/red-meat-cancer-immune/" rel="nofollow">http://blogs.discovermagazine.com/d-brief/2015/01/02/red-mea...</a>
mrestko将近 10 年前
CRISPER/Cas9 for targeted gene editing.
bootload将近 10 年前
Mary Schweitzer extracting collagen, haemoglobin, elastin, laminin from 80 million year old Hadrosaur and verifying it. [0],[1]<p>[0] 2012: <a href="http://www.nature.com/news/molecular-analysis-supports-controversial-claim-for-dinosaur-cells-1.11637" rel="nofollow">http://www.nature.com/news/molecular-analysis-supports-contr...</a><p>[1] 2009: <a href="http://www.newscientist.com/article/dn17060-first-dino-blood-extracted-from-ancient-bone.html#.VYIpCVK9azM" rel="nofollow">http://www.newscientist.com/article/dn17060-first-dino-blood...</a>
anotherevan将近 10 年前
That we basically know bugger all about nutrition.<p><a href="http://blog.dilbert.com/post/109880240641/sciences-biggest-fail" rel="nofollow">http://blog.dilbert.com/post/109880240641/sciences-biggest-f...</a>
velavar将近 10 年前
Though theoretically predicted long ago, I suppose the Higgs boson can be said to have been "discovered" in 2012 when its presence was first confirmed.
kang将近 10 年前
blockchain
Ar-Curunir将近 10 年前
Fully Homomorphic Encryption will have far reaching applications. That along with things like efficient MPC.
steven2012将近 10 年前
Preserved soft tissue was found in dinosaur bones, allowing us to see the actual structures, and apparently this is not a rare phenomenon. Maybe DNA can be extracted?
alpha1234将近 10 年前
Eugene Podkletnov gravity beam generator and TT Brown experiments showing coupling between electricity and gravitation [1].<p>[1]<a href="http://www.amazon.com/Secrets-Antigravity-Propulsion-Classified-Technology/dp/159143078X" rel="nofollow">http://www.amazon.com/Secrets-Antigravity-Propulsion-Classif...</a>
advanderveer将近 10 年前
Aminoacids in the tail of comets
AC__将近 10 年前
Vampires! Technically speaking, parabiosis. Although it is not actually a new discovery at all, personally I'm convinced there are humans who have already transfused young blood plasma(as the linked article points out illegal stem cell transplants are common as well). Yeah, that's right, vampires.<p><a href="http://www.nature.com/news/ageing-research-blood-to-blood-1.16762" rel="nofollow">http://www.nature.com/news/ageing-research-blood-to-blood-1....</a>
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stillsut将近 10 年前
Ryan Gosling and fracking.
VLM将近 10 年前
Is reality invented or discovered? Is math invented or discovered? Was automata theory invented or discovered? OK well then is the quicksort algorithm invented or discovered? Is LISP invented or discovered? Is my code invented or discovered?
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